Incomplete resection of the icEEG seizure onset zone is not associated with post-surgical outcomes [PDF]
Delineation of seizure onset regions from EEG is important for effective surgical workup. However, it is unknown if their complete resection is required for seizure freedom, or in other words, if post-surgical seizure recurrence is due to incomplete removal of the seizure onset regions. Retrospective analysis of icEEG recordings from 63 subjects (735
arxiv
The importance of early immunotherapy in patients with faciobrachial dystonic seizures. [PDF]
Faciobrachial dystonic seizures and limbic encephalitis closely associate with antibodies to leucine-rich glioma-inactivated 1 (LGI1). Here, we describe 103 consecutive patients with faciobrachial dystonic seizures and LGI1 antibodies to understand ...
Bi, Mian+15 more
core
EEG source connectivity to localize the seizure onset zone in patients with drug resistant epilepsy [PDF]
Visual inspection of the EEG to determine the seizure onset zone (SOZ) in the context of the presurgical evaluation in epilepsy is time-consuming and often challenging or impossible.
Boon, Paul+14 more
core +5 more sources
Evaluate the seizure‐reduction response and safety of brain‐responsive stimulation in adults with medically intractable partial‐onset seizures of neocortical origin.
B. Jobst+49 more
semanticscholar +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Functional and anatomic correlates of two frequently observed temporal lobe seizure-onset patterns. [PDF]
Intracranial depth electrode EEG records of 478 seizures, recorded in 68 patients undergoing diagnostic monitoring with depth electrodes, were evaluated to investigate the correlates of electrographic onset patterns in patients with temporal lobe ...
Babb, TL+3 more
core +3 more sources
Long-term treatment with responsive brain stimulation in adults with refractory partial seizures
Objective: The long-term efficacy and safety of responsive direct neurostimulation was assessed in adults with medically refractory partial onset seizures.
G. Bergey+39 more
semanticscholar +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Myelin oligodendrocyte glycoprotein antibody-associated disease presenting as unilateral cerebral cortical encephalitis: a case report [PDF]
Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an autoimmune disorder with diverse clinical manifestations including myelitis, meningitis, encephalitis, and optic neuritis.
Ji-Yoon An+6 more
doaj +1 more source