Results 121 to 130 of about 1,388,322 (334)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
THE USE OF SIMULATION AND GENETIC ALGORITHM WITH DIFFERENT GENETIC OPERATORS TO OPTIMIZE MANUFACTURING SYSTEM [PDF]
Applied Computer Science, 2013 The article depicts an evolutionary approach to simulation based optimization of a typical manufacturing system. Genetic algorithm with four different variants of genetic operators (crossover operator and type of selection) is compared to find the best ...
Tomasz WIŚNIEWSKI, Szymon RYMASZEWSKI
doaj
, 2015 Wireless sensor networks gain ample interest because of their wide range of applications. Efficient energy consumption of nodes is the prime design issue for these networks.
Vipin Pal +3 more
semanticscholar +1 more source
Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
An embedded two-layer feature selection approach for microarray data analysis
, 2009 Feature selection is an important technique in dealing with application problems with large number of variables and limited training samples, such as image processing, combinatorial chemistry, and microarray analysis.
Yang, Pengyi, Zhang, Zili
core
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
A Competitive Genetic Algorithm for Single Row Facility Layout [PDF]
The single row facility layout is the NP-Hard problem of arranging facilities with given lengths on a line, so as to minimize the weighted sum of the distances between all pairs of facilities.
Ghosh, Diptesh, Kothari, Ravi
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah +7 more
wiley +1 more source
Feature selection using a genetic algorithm-based hybrid approach
Ingeniería e Investigación, 2006 The present work proposes a hybrid feature selection model aimed at reducing training time whilst maintaining classification accuracy. The model includes adlusting a decision tree for producing feature subsets.
Luis Felipe Giraldo +3 more
doaj