Results 221 to 230 of about 3,205,265 (299)

Development and validation of a machine learning model for predicting 6-month mortality in patients with infective endocarditis. [PDF]

Biomed Eng Online
Wu X, Han Y, Liu W, Lin S, Yuan J, Ma Y, Gao C.   +6 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Greater climate change adaptation potential in populations of Quercus macrocarpa at edges of latitudinal gradient. [PDF]

New Phytol
Rea LMS, Ostrowsky L, Mohn RA, Garner M, Worcester L, Lapadat C, McCarthy HR, Hipp AL, Cavender Bares J.   +8 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Analysis of heart rate variability and subtle ECG changes based on machine learning for objective assessment of the psychological state of military personnel. [PDF]

Front Psychol
Chaikovsky I, Senko I, Budnyk M, Matsyshyn V, Ryzhenko T, Budnyk V, Romanchuk O, Popov A, Stetsyuk P.   +8 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Sudanese pearl millet (Pennisetum glaucum (L.) R. Br.) germplasm reveals genetic potential for carotenoid improvement and provitamin a biofortification. [PDF]

Sci Rep
Elkhatim KAS, Shariatipour N, Hamid MG, Muneer F, Elsafy M, Rahmatov M, Abedlhalim T.   +6 more
europepmc   +1 more source

Application of optimal contribution selection, trait distribution management, and group selection in layer chickens. [PDF]

Genet Sel Evol
Wolc A, Kinghorn BP, Kinghorn AJ, Dekkers JCM.   +3 more
europepmc   +1 more source

Development of a prediction model for the risk of prolonged ICU length of stay in patients undergoing coronary artery bypass surgery: A retrospective analysis based on the MIMIC-IV database. [PDF]

Medicine (Baltimore)
Zhang P, Zhang X, Wang J, Zhang Y.
europepmc   +1 more source

Health and Socio-Economic Impacts of Climate-Related Displacement in Bangladesh's Chars: Causal Evidence From a Household Survey. [PDF]

Int J Public Health
de Castro JA, Guinea L.
europepmc   +1 more source