Results 101 to 110 of about 953,385 (274)

Portfolio selection problems in practice: a comparison between linear and quadratic optimization models

, 2010
Several portfolio selection models take into account practical limitations on the number of assets to include and on their weights in the portfolio.
A Fernández, A Meucci, A Schaerf, A Scozzari, AD Roy, Andrea Scozzari, C Acerbi, C Acerbi, CI Fábián, D Bertsimas, D Bertsimas, D Bienstock, D Lorenzo Di, D Maringer, DX Shawa, E Angelelli, EJ Elton, F Cesarone, F Cesarone, F Tardella, F Tardella, Fabio Tardella, Francesco Cesarone, G Mitra, H Kellerer, H Konno, H Konno, H Konno, HM Markowitz, IM Bomze, JE Beasley, KP Anagnostopoulos, L Chiodi, L Gaspero Di, MG Speranza, MG Speranza, NA Canakgoz, NJ Jobst, P Artzner, R Bruni, R Bruni, R Mansini, R Mansini, R Mansini, RT Rockafellar, RT Rockafellar, ST Rachev, TJ Chang   +47 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Morpho-physiological characterization and selection of heat tolerant wheat lines using selection indices

Electronic Journal of Plant Breeding
Heat stress is one of the major constraints in wheat production due to its adverse effect on grain yield and component traits. Moreover, it negatively affects the physiological, biochemical and quality traits of wheat.
Satender Yadav1*, Vikram Singh1, Hari Kesh2, Anu Naruka3, Mukesh Kumar1, Virender Singh Mor1 and Shikha Yashveer1
doaj   +1 more source

Report on selected indicators

, 2020
In this report a set of indicators is proposed for summarizing objectives and providing up-to-date information on the impacts of climate change, the state-of-the-environment and societal conditions of islands. These indicators are meant to support a practical description.
Lionello, Piero, Bacciu, Valentina, Briche, Elodie, Dubois, Ghislain, Hernandez, Matias Gonzalez, Gaertner, Miguel Angel, Ruiz Valdepenas, Lora, Veronica, Hoevenaars, Kyra, Galindo, Carmen Garcia, Suarez, Salvador, Freitas, Ricardo Meneses   +11 more
openaire   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Hedge fund portfolio selection with modified expected shortfall [PDF]

Modified Value-at-Risk (VaR) and Expected Shortfall (ES) are recently introduced downside risk estimators based on the Cornish-Fisher expansion for assets such as hedge funds whose returns are non-normally distributed.
Boudt, Kris, Carl, Peter, Peterson, Brian   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Optimising multistage dairy cattle breeding schemes including genomic selection using decorrelated or optimum selection indices

Genetics Selection Evolution, 2012
Background The prediction of the outcomes from multistage breeding schemes is especially important for the introduction of genomic selection in dairy cattle.
Börner Vinzent, Reinsch Norbert
doaj   +1 more source

The statistical theory of linear selection indices from phenotypic to genomic selection. [PDF]

Crop Sci, 2022
Cerón-Rojas JJ, Crossa J.
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source