Results 111 to 120 of about 953,385 (274)

Effects of Imported Semen Based on Different Selection Indices on Some Production and Reproduction Traits in Iranian Holstein Cattle. [PDF]

Animals (Basel), 2022
Nazari M, Mahmoudi P, Rashidi A, Razmkabir M.   +3 more
europepmc   +1 more source

Coconut breeding in Sri Lanka:a review [PDF]

, 1988
Work done by Coconut Research Institute, Sri Lanka, on the genetics and breeding of the coconut palm from 1930 to 1980 is described.It involves studies on; mass selection methods, selection differential, progeny trials, inbreeding depression, estimation ...
Jayasekara, C., Liyanage, D.V., Wickramaratne, M.R.T.   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Genetic selection indices for growth traits in Blanco-Orejinegro cattle. [PDF]

Transl Anim Sci, 2021
Ramírez Toro EJ, Mourão GB, Martínez Sarmiento RA, Cerón-Muñoz MF.   +3 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Identification of Spring Wheat with Superior Agronomic Performance under Contrasting Nitrogen Managements Using Linear Phenotypic Selection Indices. [PDF]

Plants (Basel), 2022
Iqbal M, Semagn K, Céron-Rojas JJ, Crossa J, Jarquin D, Howard R, Beres BL, Strenzke K, Ciechanowska I, Spaner D.   +9 more
europepmc   +1 more source

Non-market Leadership Experience and Labor Market Success : Evidence From Military Rank [PDF]

There has been much recent interest in the effects of pre and non-market skills on future labor market outcomes. This paper examines one such effect : the effect on future wages of military leadership experience among "Vietnam generation" American men ...
Chun Seng Yip, Myoung-Jae Lee
core   +1 more source

Adapting the Interrelated Two-way Clustering method for Quantitative Structure-Activity Relationship (QSAR) Modeling of a Diverse Set of Chemical Compounds

, 2013
Interrelated Two-way Clustering (ITC) is an unsupervised clustering method developed to divide samples into two groups in gene expression data obtained through microarrays, selecting important genes simultaneously in the process.
Basak, Subhash C., Grunwald, Gregory D., Majumdar, Subhabrata   +2 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source