Results 111 to 120 of about 957,890 (293)

Portfolio selection problems in practice: a comparison between linear and quadratic optimization models

open access: yes, 2010
Several portfolio selection models take into account practical limitations on the number of assets to include and on their weights in the portfolio.
A Fernández   +47 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Genetic selection indices for growth traits in Blanco-Orejinegro cattle. [PDF]

open access: yesTransl Anim Sci, 2021
Ramírez Toro EJ   +3 more
europepmc   +1 more source

Approximating the Growth Optimal Portfolio with a Diversified World Stock Index [PDF]

open access: yes
This paper constructs and compares various total return world stock indices based on daily data. Due to diversification these indices are noticeably similar. A diversification theorem identifies any diversified portfolio as a proxy for the growth optimal
Eckhard Platen, Truc Le
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Identification of Spring Wheat with Superior Agronomic Performance under Contrasting Nitrogen Managements Using Linear Phenotypic Selection Indices. [PDF]

open access: yesPlants (Basel), 2022
Iqbal M   +9 more
europepmc   +1 more source

Coconut breeding in Sri Lanka:a review [PDF]

open access: yes, 1988
Work done by Coconut Research Institute, Sri Lanka, on the genetics and breeding of the coconut palm from 1930 to 1980 is described.It involves studies on; mass selection methods, selection differential, progeny trials, inbreeding depression, estimation ...
Jayasekara, C.   +2 more
core  

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