Results 81 to 90 of about 957,890 (293)

A Comparison of Parametric and Non-Parametric Selection Indices for Selecting Corn Hybrids in the Brazilian Cerrado

Agronomy
The selection of superior maize genotypes is complex due to the quantitative and intercorrelated nature of agronomic traits and their strong environmental influence, which limits the efficiency of direct selection and requires multivariate approaches ...
Felipe Zôrzo, Renato Fernando Amabile, Carolaini Campos da Silva, Juaci Vitória Malaquias, João Victor Pinheiro Melo, Arlini Rodrigues Fialho, Bárbara Soares Aires França, Marcelo Fagioli   +7 more
doaj   +1 more source

Genetic parameters and line selection of Cucurbita pepo based on selection indices

Bioscience Journal, 2020
In the improvement of pumpkins, the selection based on one or a few characters of interest tends to be less efficient, leading to a superior product only compared to the few characters selected.
Igor Forigo Beloti, Gabriel Mascarenhas Maciel, Fernando Cezar Juliatti, Rafael Resende Finzi, Daniel Bonifácio Oliveira Cardoso   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Selection Indices in Indian Mustard [Brassica juncea (L.) Czern & Coss] [PDF]

Electronic Journal of Plant Breeding, 2013
The discriminant-function technique was used to construct selection indices in 50 genotypes of Indian mustard (Brassica juncea). Sixty-three selection indices involving seed yield per plant and its five components were constructed using discriminant ...
V.B. Rathod, D.R. Mehta*, H.V. Solanki and L.J. Raval
doaj  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Optimising desired gain indices to maximise selection response

Frontiers in Plant Science
IntroductionIn plant breeding, we often aim to improve multiple traits at once. However, without knowing the economic value of each trait, it is hard to decide which traits to focus on.
Reem Joukhadar, Yongjun Li, Rebecca Thistlethwaite, Kerrie L. Forrest, Josquin F. Tibbits, Richard Trethowan, Richard Trethowan, Matthew J. Hayden, Matthew J. Hayden   +8 more
doaj   +1 more source

Simultaneous selection in progenies of yellow passion fruit using selection indices

Revista Ceres, 2012
This study aimed to evaluate the efficiency of simultaneous selection (selection indices) using estimated genetic gains in yellow passion fruit and to make a comparison between the methodologies of Mulamba & Mock and Elston.
Luciana Domiciano Silva Rosado, Carlos Eduardo Magalhães dos Santos, Claudio Horst Bruckner, Endson Santana Nunes, Cosme Damião Cruz   +4 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Selection indices for yield in rabi sorghum (Sorghum bicolor L. Moench) genotypes [PDF]

Electronic Journal of Plant Breeding, 2012
Various selection indices were constructed for yield in rabi sorghum genotypes using 45 genotypes. Among various traits,plant height, 1000-seed weight and fodder yield had significant and positive genotypic correlation with the seed yield perplant. Among
C.V.Sameer Kumar, Ch.Sreelakshmi and D.Shivani
doaj