Results 81 to 90 of about 953,385 (274)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Selection Indices in Indian Mustard [Brassica juncea (L.) Czern & Coss] [PDF]

Electronic Journal of Plant Breeding, 2013
The discriminant-function technique was used to construct selection indices in 50 genotypes of Indian mustard (Brassica juncea). Sixty-three selection indices involving seed yield per plant and its five components were constructed using discriminant ...
V.B. Rathod, D.R. Mehta*, H.V. Solanki and L.J. Raval
doaj  

A new search for distant radio galaxies in the southern hemisphere - I. Sample definition and radio properties

, 2007
This paper introduces a new program to find high-redshift radio galaxies in the southern hemisphere through ultra-steep spectrum (USS) selection. We define a sample of 234 USS radio sources with spectral indices alpha_408^843 < -1.0 and flux densities ...
Athreya, Barthel, Baugh, Blumenthal, Blundell, Blundell, Bock, Bornancini, Bower, Broderick, Burgess, Burgess, Carilli, Carilli, Chambers, Cohen, Cohen, Cole, Colless, Condon, Condon, Cruz, De Breuck, De Breuck, De Breuck, De Breuck, De Breuck, De Propris, E. M. Sadler, Eales, Fan, Fan, Fanaroff, Frater, Gardner, Gebhardt, Hambly, Inskip, J. J. Bryant, J. W. Broderick, Jarvis, Johnston-Hollitt, Jones, Kauffmann, Klamer, Krolik, Large, Lumsden, Matthews, Mauch, McGreer, McLure, Mesa, Mills, Mills, Neeser, O'Dea, Pentericci, R. W. Hunstead, Robertson, Rocca-Volmerange, Röttgering, Sault, Somerville, Spergel, T. Murphy, Thompson, Tielens, Tucci, Van Breugel, Van Breugel, Venturi, Willott   +72 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Optimising desired gain indices to maximise selection response

Frontiers in Plant Science
IntroductionIn plant breeding, we often aim to improve multiple traits at once. However, without knowing the economic value of each trait, it is hard to decide which traits to focus on.
Reem Joukhadar, Yongjun Li, Rebecca Thistlethwaite, Kerrie L. Forrest, Josquin F. Tibbits, Richard Trethowan, Richard Trethowan, Matthew J. Hayden, Matthew J. Hayden   +8 more
doaj   +1 more source

Simultaneous selection in progenies of yellow passion fruit using selection indices

Revista Ceres, 2012
This study aimed to evaluate the efficiency of simultaneous selection (selection indices) using estimated genetic gains in yellow passion fruit and to make a comparison between the methodologies of Mulamba & Mock and Elston.
Luciana Domiciano Silva Rosado, Carlos Eduardo Magalhães dos Santos, Claudio Horst Bruckner, Endson Santana Nunes, Cosme Damião Cruz   +4 more
doaj   +1 more source

A genetic and economic evaluation of lactose in the New Zealand dairy industry : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science [PDF]

, 2016
Milk composition in New Zealand is heavily influenced by the selection for Breeding Worth (BW) and the breed composition of the national herd. Under selection for BW a greater emphasis is placed upon protein (39% of emphasis) than fat yield (13% of ...
Sneddon, Nicholas William
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Selection indices for yield in rabi sorghum (Sorghum bicolor L. Moench) genotypes [PDF]

Electronic Journal of Plant Breeding, 2012
Various selection indices were constructed for yield in rabi sorghum genotypes using 45 genotypes. Among various traits,plant height, 1000-seed weight and fodder yield had significant and positive genotypic correlation with the seed yield perplant. Among
C.V.Sameer Kumar, Ch.Sreelakshmi and D.Shivani
doaj  

Selection indices in groundnut (Arachis hypogaea L.)

Electronic Journal of Plant Breeding, 2016
Fifty diverse genotypes of groundnut were evaluated in a randomized block design with three replications for the study of selection indices during summer 2014. Thirty-one selection indices involving pod yield per plant (X1) and four yield components viz.,
Satyendra Singh Raghuwanshi, V. H. Kachadia, J. H. Vachhani, L. L. Jivani, Ashok Kumar Malav and, Shakti Singh Bhati   +5 more
doaj   +1 more source