Results 171 to 180 of about 3,596,398 (274)

Oscillator Selection Strategies to Optimize a Physically Unclonable Function for IoT Systems Security. [PDF]

Sensors (Basel), 2023
Aparicio-Téllez R, Garcia-Bosque M, Díez-Señorans G, Celma S.   +3 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Benchmark study of feature selection strategies for multi-omics data. [PDF]

BMC Bioinformatics, 2022
Li Y, Mansmann U, Du S, Hornung R.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Feature Selection Strategies for Deep Learning-Based Classification in Ultra-High-Dimensional Genomic Data. [PDF]

Int J Mol Sci
Kotlarz K, Słomian D, Zawadzka W, Szyda J.   +3 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Comparing variable and feature selection strategies for prediction - protocol of a simulation study in low-dimensional transplantation data. [PDF]

PLoS One
Hoessly L, Frossard J, Schwab S, Chammartin F, Leichtle A, Schreiber PW, Neofytos D, Koller M, with the Swiss Transplant Cohort Study (STCS).   +8 more
europepmc   +1 more source

Astrocyte activities in the external globus pallidus regulate action-selection strategies in reward-seeking behaviors. [PDF]

Sci Adv, 2023
Kang S, Hong SI, Kang S, Song M, Yang MA, Essa H, Baker M, Lee J, Bruce RA, Lee SW, Choi DS.   +10 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Analysis of different genotyping and selection strategies in laying hen breeding programs. [PDF]

Genet Sel Evol
Büttgen L, Simianer H, Pook T.
europepmc   +1 more source