Results 171 to 180 of about 11,499,836 (351)
Combining svms with various feature selection strategies
, 2005 Summary. This article investigates the performance of combining support vector machines (SVM) and various feature selection strategies. Some of them are filtertype approaches: general feature selection methods independent of SVM, and some are wrapper ...
Yi-wei Chen, Chih-jen Lin
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Novel Relay Selection Strategies for Cooperative NOMA
IEEE Transactions on Vehicular Technology, 2017 Zhengju Yang, Z. Ding, Yi Wu, P. Fan
semanticscholar +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A knowledge-based decision support system for roofing materials selection
, 2009 Varieties of materials are available for roof housing construction but selecting the appropriate material is a complex and ponderous task. In order to choose the right material, a multitude of performance criteria would need to be considered.
Rahman, Sazzadur +5 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Opportunity Costs, Competition, and Firm Selection [PDF]
The paper questions the standard economic assumptions that competing economic agents have identical reservation utility levels, and that when differences in opportunity costs exit, they can be conveniently represented by fixed costs.
Gamal Atallah
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Selection and mating strategies risks and rewards
, 2010 Best Linear Unbiassed Prediction provides a valuable mechanism through which effective selection practices can operate, potentially enhancing performance and producing significant increases in productivity and thus, frequently in profitability.
Klieve, Helen Margaret +2 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source