Results 51 to 60 of about 11,499,836 (351)

Multiple-input multiple-output causal strategies for gene selection

open access: yesBMC Bioinformatics, 2011
Background Traditional strategies for selecting variables in high dimensional classification problems aim to find sets of maximally relevant variables able to explain the target variations.
Bontempi Gianluca   +4 more
doaj   +1 more source

Strategy and Sample Selection: A Strategic Selection Estimator [PDF]

open access: yesPolitical Analysis, 2014
The development and proliferation of strategic estimators has narrowed the gap between theoretical models and empirical testing. But despite recent contributions that extend the basic strategic estimator, researchers have continued to neglect a classic social science phenomenon: selection.
openaire   +4 more sources

Feature selection strategies for drug sensitivity prediction

open access: yesScientific Reports, 2019
Drug sensitivity prediction constitutes one of the main challenges in personalized medicine. Critically, the sensitivity of cancer cells to treatment depends on an unknown subset of a large number of biological features.
Krzysztof Koras   +5 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Selected synthetic strategies to cyclophanes [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2015
In this review we cover various approaches to meta- and paracyclophanes involving popular reactions. Generally, we have included a strategy where the reaction was used for assembling the cyclophane skeleton for further functionalization. In several instances, after the cyclophane is made several popular reactions are used and these are not covered here.
KOTHA, S, SHIRBHATE, ME, WAGHULE, GT
openaire   +4 more sources

Selection Does Not Operate Primarily on Genes [PDF]

open access: yes, 2008
This chapter offers a review of standard views about the requirements for natural selection to shape evolution and for the sorts of ‘units’ on which selection might operate.
Burian, Richard
core  

Prediction of breeding values and selection responses with genetic heterogeneity of environmental variance [PDF]

open access: yes, 2007
There is empirical evidence that genotypes differ not only in mean, but also in environmental variance of the traits they affect. Genetic heterogeneity of environmental variance may indicate genetic differences in environmental sensitivity.
Mulder, H. A.   +7 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Diagnostic Strategies for Treatment Selection in Advanced Prostate Cancer

open access: yesDiagnostics, 2021
Prostate Cancer (PCa) is a leading cause of morbidity and mortality among men worldwide. For most men with PCa, their disease will follow an indolent course. However, advanced PCa is associated with poor outcomes.
Ciara S. McNevin   +3 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

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