Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Sex-stratified compositional analysis of 24-h movement behaviors and their relationship with selective attention and cognitive flexibility in socioeconomically vulnerable children. [PDF]
Muñoz-Pardeza J +8 more
europepmc +1 more source
The Selectivity of Task-Dependent Attention Varies with Surrounding Context [PDF]
Yee‐Joon Kim, Preeti Verghese
openalex +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Examining the Relationship Between Early Experience, Selective Attention, and the Formation of Learning Traps. [PDF]
Liu Y, Newell BR, Lee JE, Hayes BK.
europepmc +1 more source
Selective attention to change/no-change in color and shape
Motohiro Kimura +2 more
openalex +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Brain dynamics of the interplay between auditory selective attention and working memory during melody encoding. [PDF]
de la Chapelle A +8 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
How musicality enhances top-down and bottom-up selective attention: Insights from precise separation of simultaneous neural responses. [PDF]
Manting CL +3 more
europepmc +1 more source

