Results 111 to 120 of about 1,301,823 (301)

Exposure to diverse political views in contemporary media environments

open access: yesFrontiers in Communication
Exploring the nexus between digital media and citizens’ exposure to diverse political views is imperative for understanding contemporary democratic engagement.
Nili Steinfeld, Azi Lev-on
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Development of low cost, high reliability sealing techniques for hybrid microcircuit packages, phase 2 [PDF]

open access: yes
Adhesives were evaluated to determine if they qualify for application to hybrid microcircuit packages. The effort consisted of the following: (1) seal gold-plated Kovar packages with selective adhesives and determine seal integrity after exposure to ...
Licari, J. J., Perkins, K. L.
core   +1 more source

Counterparty Credit Limits: An Effective Tool for Mitigating Counterparty Risk?

open access: yes, 2020
A counterparty credit limit (CCL) is a limit imposed by a financial institution to cap its maximum possible exposure to a specified counterparty. Although CCLs are designed to help institutions mitigate counterparty risk by selective diversification of ...
Gould, Martin D.   +3 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Migration and generation of contaminants from launch through recovery: LDEF case history [PDF]

open access: yes
It is possible to recreate the contamination history of the Long Duration Exposure Facility (LDEF) through an analysis of its contaminants and selective samples that were collected from surfaces with better documented exposure histories.
Crutcher, E. R.   +3 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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