Selective information sampling [PDF]
This study investigates the amount and valence of information selected during single item evaluation. One hundred and thirty-five participants evaluated a cell phone by reading hypothetical customers reports. Some participants were first asked to provide
Peter A. F. Fraser-Mackenzie +1 more
doaj
Selective information sampling: Cognitive coherence in evaluation of a novel item
This study investigates the amount and valence of information selected during single item evaluation. One hundred and thirty-five participants evaluated a cell phone by reading hypothetical customers reports. Some participants were first asked to provide
Peter A. F. Fraser-Mackenzie +1 more
doaj +1 more source
Analysis of the visual spatiotemporal properties of American Sign Language. [PDF]
Careful measurements of the temporal dynamics of speech have provided important insights into phonetic properties of spoken languages, which are important for understanding auditory perception.
Bosworth, Rain G +2 more
core
In-situ tuning of individual position-controlled nanowire quantum dots via laser-induced intermixing
We demonstrate an in-situ technique to tune the emission energy of semiconductor quantum dots. The technique is based on laser-induced atomic intermixing applied to nanowire quantum dots grown using a site-selective process that allows for the ...
Aers, Geof C. +6 more
core +1 more source
Uptake, accumulation and metabolization of the antidepressant fluoxetine by Mytilus galloprovincialis [PDF]
Fluoxetine, a selective serotonin re-uptake inhibitor (SSRI) antidepressant, is among the most prescribed pharmaceutical active substances worldwide. This study aimed to assess its accumulation and metabolization in the mussel Mytillus galloprovincialis,
André M.P.T. Pereira +39 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53 independent pathways [PDF]
Most cancer cells use aerobic glycolysis to fuel their growth. The enzyme lactate dehydrogenase-A (LDH-A) is key to cancer’s glycolytic phenotype, catalysing the regeneration of nicotinamide adenine dinucleotide (NAD þ ) from reduced nicotinamide adenine
Allison, Simon J. +6 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout. [PDF]
ObjectiveLesinurad (LESU) is a selective urate reabsorption inhibitor approved at 200 mg daily for use with a xanthine oxidase inhibitor (XOI) to treat hyperuricaemia in gout patients failing to achieve target serum urate on XOI. The aim of the study was
Baumgartner, Scott +8 more
core +1 more source
High Speed Sintering – Continuing Research into a New Rapid Manufacturing Process [PDF]
High Speed Sintering (HSS) is an emerging layer manufacturing technique aiming to break into the lucrative field of Rapid Manufacturing (RM). The process is likened to Selective Laser Sintering (SLS), however, instead of a laser dictating the sintered ...
Erasenthiran, Poonjolai +2 more
core +1 more source

