Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On abolishing symmetry requirements in the formulation of a five-level selective harmonic elimination pulse-width modulation technique [PDF]
Selective harmonic elimination pulse width modulation (SHE-PWM) techniques offer a tight control of the harmonic spectrum of a given voltage waveform generated by a power electronic converter along with a low number of switching transitions.
Rao, M.V. +2 more
core
Fast and fault‐tolerant model predictive control of MMCs under selective harmonic elimination
Selective harmonic elimination (SHE) is a suitable pulse‐width modulation (PWM) technique for some applications of modular multilevel converters (MMC) with lower number of semiconductor submodules (SM).
Ardavan Mohammadhassani +1 more
doaj +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Five-level selective harmonic elimination PWM strategies and multicarrier phase-shifted sinusoidal PWM: A comparison [PDF]
The multicarrier phase-shifted sinusoidal pulse-width modulation (MPS-SPWM) technique is well-known for its important advantage of offering an increased overall bandwidth as the number of carriers multiplied with their equal frequency directly controls ...
Cossar, C. +3 more
core
FPGA Based Selective Harmonic Elimination Technique for Multilevel Inverter [PDF]
Harmonic elimination at the fundamental frequency is very much appropriate for high and medium range of power generation and applications. This paper considers a new technique for selective harmonic elimination (SHE), in which the total harmonic ...
Porselvi, T. +5 more
core +1 more source
Dynamic and Steady State Response Analysis of Selective Harmonic Elimination in High Power Inverters
Selective harmonic elimination (SHE) technique has drawn tremendous interests for its superior harmonic performance, especially in high power devices where switching power loss and passive filter size are the main concerns. However, the drawbacks of slow
Jingling Cheng +3 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source

