Results 91 to 100 of about 940,941 (306)

Internal Perspectivalism: The Solution to Generality Problems About Proper Function and Natural Norms [PDF]

, 2020
In this paper, I argue that what counts as the proper function of a trait is a matter of the de facto perspective that the biological system, itself, possesses on what counts as proper functioning for that trait.
Winning, Jason
core   +2 more sources

The selective advantage of reaction norms for environmental tolerance [PDF]

, 1992
A tolerance curve defines the dependence of a genotype's fitness on the state of an environmental gradient. It can be characterized by a mode (the genotype's optimal environment) and a width (the breadth of adaptation). It seems possible that one or both
Gabriel, Wilfried, Lynch, Michael
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Alcohol, nutrition and health maintenance: selected aspects [PDF]

Proceedings of the Nutrition Society, 2004
In view of the developments in health care relating to the increased prevalence and incidence of chronic diseases and the continuing increase in health-care expenditure, more attention should be paid to health maintenance and disease prevention. Any strategy that can influence health maintenance is of interest, especially lifestyle factors such as ...
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Electrochemical impedance spectroscopy as a tool for probing the functionality of ion-selective membranes [PDF]

, 2009
Recent success in lowering of the detection limit of ion-selective electrodes (ISEs) to part-perbillion levels have opened up the possibility for their application in environmental analysis.
Anastasova, Salzitsa, Bobacka, Johan, Danielewski, Marek, Diamond, Dermot, Lewenstam, Andrzej, Paczosa-Bator, Beata, Radu, Aleksandar   +6 more
core  

One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases [PDF]

, 2015
Understanding the complex population biology and transmission ecology of multihost parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most ...
Adamo, Akopyants, Anderson, Antia, Azevedo, Berry, Betson, Biswas, Boatin, Boissier, Chargui, Civetello, Cleaveland, Combes, Consortium* THG, Crichton, Criscione, Cutillas, Delgado, Detwiler, Dobson, Doby, Dunams-Morel, Eberhard, Fan, Faye, Fenton, Fenton, Fraga de Azevedo, Funk, Garba, Gaunt, Gelanew, Genis, Gibbs, Gibson, Gouvras, Gretillat, Grigg, Gupta, Hahn, Hahn, Hanelt, Hargrove, Haydon, Hotez, Hotez, Huyse, Huyse, Inpankaew, Johnson, Jolles, Kaushik, Kaushik, Keesing, Kelly, Kilpatrick, King, Klepac, Koukounari, Lamberton, Laval, Le, Leger, Lembo, Liang, Liese, Lloyd-Smith, Lu, Lu, Lu, Lu, Lustigman, Machado, Maia, Mathews, Mavarez, Messenger, Messenger, Miles, Molyneux, Moné, Muhanguzi, Muller-Graf, Mupfasoni, Norton, Pardo-Diaz, Parrish, Pedersen, Perez-Quintero, Ramiro, Randolph, Ravel, Robinson, Rogers, Rollinson, Rudge, Rudge, Rudge, Salkeld, Saroufim, Silva Oliveira, Smith, Steinauer, Strauss, Streicker, Streicker, Sturm, Taylor, Theron, Theron, Tomley, UNDP, Viana, Volf, Wang, Webby, Webster, Webster, Webster, Webster, Webster, Webster, Welburn, Welburn, Whitlock, WHO, Wood, Woolhouse, Woolhouse, Woolhouse, Woolhouse, Woolhouse, Yamane, Yamane, Zhou   +135 more
core   +5 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Selective Requirement for Maintenance of Synaptic Contacts onto Motoneurons by Target-Derived trkB Receptors

Neural Plasticity, 2016
Synaptic contacts onto motoneurons were studied in mice in which the gene for the trkB neurotrophin receptor was knocked out selectively in a subset of spinal motoneurons.
Xiya Zhu, Patricia J. Ward, Arthur W. English   +2 more
doaj   +1 more source

Case Report: Evaluation strategies and cognitive intervention: the case of a monovular twin child affected by selective mutism [version 1; referees: 2 approved]

F1000Research, 2018
The present work describes the assessment process, evaluation strategies, and cognitive intervention on a 9 years old child with selective mutism (SM), a monovular twin of a child also affected by mutism.
Micaela Capobianco, Luca Cerniglia
doaj   +1 more source