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Selective Serotonin Reuptake Inhibitors and Solitary Rectal Ulcer Syndrome: A Bloody Relationship. [PDF]
Eur J Case Rep Intern MedMoussallem N +4 more
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Selective Serotonin Reuptake Inhibitors
Handbook of Experimental Pharmacology, 2018The first antidepressants were created by chance but brought the idea that central serotonin agonism produced an antidepressant effect. SSRIs were the first class of psychotropic medications to be rationally designed, meaning that researchers intended to utilize a specific mechanism of action while avoiding adverse effects.
Dee, Lochmann, Tara, Richardson
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American Journal of Obstetrics and Gynecology, 2019 BACKGROUND: There is a marked increase in the use of selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors in the last decade. Many newborns are likely to be exposed during pregnancy and labor.
Reem Masarwa +2 more
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The Pharmacogenomics of Selective Serotonin Reuptake Inhibitors
Pharmacogenomics, 2022Antidepressant medications are frequently used as the first line of treatment for depression. However, their effectiveness is highly variable and influenced by genetic factors. Recently, pharmacogenetic studies, including candidate-gene, genome-wide association studies or polygenic risk scores, have attempted to uncover the genetic architecture of ...
Luis M García-Marín +5 more
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Clinical Gastroenterology and Hepatology, 2015 Hai-Yin Jiang, Min Deng, Bing Ruan
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Selective Serotonin Reuptake Inhibitors in Pregnancy
Current Medicinal Chemistry, 2012The use of antidepressant drugs, such as selective serotonin reuptake inhibitors (SSRIs), during pregnancy is rapidly increasing. To date, the effects of SSRI on pregnant women and fetuses are controversial and still a matter of debate. Although a number of studies have shown that these antidepressants are not teratogenic, some of them have reported an
Bellissima, V. +3 more
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Selective Serotonin-Reuptake Inhibitors: An Update
Harvard Review of Psychiatry, 1999Selective serotonin-reuptake inhibitors (SSRIs), including fluoxetine, sertraline, paroxetine, fluvoxamine, and citalopram, represent an important advance in the pharmacotherapy of mood and other disorders. They are chemically unrelated to tricyclic, heterocyclic, and other first-generation antidepressants.
P S, Masand, S, Gupta
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Selective Serotonin Reuptake Inhibitor Exposure
Topics in Companion Animal Medicine, 2013Many antidepressants inhibit serotonin or norepinephrine reuptake or both to achieve their clinical effect. The selective serotonin reuptake inhibitor class of antidepressants (SSRIs) includes citalopram, escitalopram (active enantiomer of citalopram), fluoxetine, fluvoxamine, paroxetine, and sertraline.
Kevin T, Fitzgerald, Alvin C, Bronstein
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Clastogenicity of selective serotonin-reuptake inhibitors
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2004Selective serotonin-reuptake inhibitors (SSRIs) are used in the treatment of various forms of psychiatric disorders. Preclinical studies in laboratory animals have indicated that SSRIs were not genotoxic, but clear results from in vitro testing of SSRIs in a human cell system are currently scarce.
Gokay, Bozkurt +8 more
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