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A large fraction of the genome of all organisms studied to date is subject to mutations that are effectively neutral with respect to their fitness effects, and hence evolve under genetic drift, as described by the neutral theory. In an extended version, this theory also agrees with the observation that the great majority of newly arising mutations that
Wolfgang Stephan, Pavlos Pavlidis
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Wolfgang Stephan, Pavlos Pavlidis
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Anion‐selective exhaustive injection‐sweeping microemulsion electrokinetic chromatography
ELECTROPHORESIS, 2006AbstractIn this study, anion‐selective exhaustive injection‐sweeping (ASEI‐sweeping) technique, which is a selective on‐line sample concentration technique, was first proposed in microemulsion electrokinetic chromatography (MEEKC) for analyses of eight acidic phenolic compounds.
Hsi-Ya, Huang +2 more
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Fast and robust detection of ancestral selective sweeps
Molecular Ecology, 2017AbstractThere are few methods tailored for detecting signals of positive selection in populations directly ancestral to multiple descendent populations. We introduce the ancestral branch statistic (ABS), a four‐population summary statistic for identifying selective sweeps occurring in the direct ancestor of a pair of populations.
Xiaoheng Cheng +2 more
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Anion selective exhaustive injection-sweep–micellar electrokinetic chromatography
Journal of Chromatography A, 2001A selective on-line sample concentration technique of anion selective exhaustive injection (ASEI)-sweep-micellar electrokinetic chromatography (MEKC) was evaluated using a cationic surfactant. To suppress the electroosmotic flow, a polyacrylamide-coated capillary was introduced.
J B, Kim, K, Otsuka, S, Terabe
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Haplotype-based analysis of selective sweeps in sheep
Genome, 2014Domestic animals represent an extremely useful model for linking genotypic and phenotypic variation. One approach involves identifying allele frequency differences between populations, using FST, to detect selective sweeps. While simple to calculate, FST may generate false positives due to aspects of population history.
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Statistical Methods for Detecting Selective Sweeps
2014The emigration of humankind from Africa and the adoption of agriculture have meant that the selective pressures on humankind have changed in recent evolutionary times. A selective sweep occurs when a positive mutation spreads through a population. For example, a mutation that enables adults to digest lactase has spread through the Northern European ...
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