A survey of methods and tools to detect recent and strong positive selection
Positive selection occurs when an allele is favored by natural selection. The frequency of the favored allele increases in the population and due to genetic hitchhiking the neighboring linked variation diminishes, creating so-called selective sweeps ...
Pavlos Pavlidis, Nikolaos Alachiotis
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A selective sweep of >8 Mb on chromosome 26 in the Boxer genome
Background Modern dog breeds display traits that are either breed-specific or shared by a few breeds as a result of genetic bottlenecks during the breed creation process and artificial selection for breed standards.
Altet Laura +7 more
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Selective sweep in the Flotillin-2 region of European Drosophila melanogaster. [PDF]
Localizing genes that are subject to recent positive selection is a major goal of evolutionary biology. In the model organism Drosophila melanogaster many attempts have been made in recent years to identify such genes by conducting so-called genome scans
Annegret Werzner +4 more
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Localizing recent adaptive evolution in the human genome.
Identifying genomic locations that have experienced selective sweeps is an important first step toward understanding the molecular basis of adaptive evolution.
Scott H Williamson +5 more
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The strong selective sweep candidate gene ADRA2C does not explain domestication related changes in the stress response of chickens. [PDF]
Analysis of selective sweeps to pinpoint causative genomic regions involved in chicken domestication has revealed a strong selective sweep on chromosome 4 in layer chickens.
Magnus Elfwing +4 more
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Gene connectivity and enzyme evolution in the human metabolic network
Background Determining the factors involved in the likelihood of a gene being under adaptive selection is still a challenging goal in Evolutionary Biology. Here, we perform an evolutionary analysis of the human metabolic genes to explore the associations
Begoña Dobon +4 more
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approaches to discover the functional impact of non-synonymous single nucleotide polymorphisms in selective sweep regions of the Landrace genome [PDF]
Objective The aim of this study was to discover the functional impact of non-synonymous single nucleotide polymorphisms (nsSNPs) that were found in selective sweep regions of the Landrace genome Methods Whole-genome re-sequencing data were obtained from ...
Donghyun Shin +2 more
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Predicting Carriers of Ongoing Selective Sweeps without Knowledge of the Favored Allele. [PDF]
Methods for detecting the genomic signatures of natural selection have been heavily studied, and they have been successful in identifying many selective sweeps.
Roy Ronen +5 more
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Identification of selection signatures in livestock species
The identification of regions that have undergone selection is one of the principal goals of theoretical and applied evolutionary genetics. Such studies can also provide information about the evolutionary processes involved in shaping genomes, as well as
João José de Simoni Gouveia +3 more
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IntroductionClimate changes pose a significant threat to crop adaptation and production. Dissecting the genetic basis of phenotypic plasticity and uncovering the responsiveness of regulatory genes to environmental factors can significantly contribute to ...
Yuting Ma +8 more
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