Selective sweeps in SARS-CoV-2 variant competition
The main mathematical result in this paper is that change of variables in the ordinary differential equation (ODE) for the competition of two infections in a Susceptible–Infected–Removed (SIR) model shows that the fraction of cases due to the new variant satisfies the logistic differential equation, which models selective sweeps.
Boyle, Laura +6 more
openaire +3 more sources
Modelling chemical reactions using semiconductor quantum dots [PDF]
We propose using semiconductor quantum dots for a simulation of chemical reactions as electrons are redistributed among such artificial atoms. We show that it is possible to achieve various reaction regimes and obtain different reaction products by ...
A. Yu. Smirnov +4 more
core +2 more sources
A novel locus on chromosome 1 underlies the evolution of a melanic plumage polymorphism in a wild songbird [PDF]
Understanding the mechanisms responsible for phenotypic diversification within and among species ultimately rests with linking naturally occurring mutations to functionally and ecologically significant traits.
Yann X. C. Bourgeois +13 more
doaj +1 more source
Genetic drift at expanding frontiers promotes gene segregation [PDF]
Competition between random genetic drift and natural selection plays a central role in evolution: Whereas non-beneficial mutations often prevail in small populations by chance, mutations that sweep through large populations typically confer a selective ...
Cavalli-Sforza +15 more
core +2 more sources
Fixation probability for competing selective sweeps
We consider a biological population in which a beneficial mutation is undergoing a selective sweep when a second beneficial mutation arises at a linked locus and we investigate the probability that both mutations will eventually fix in the population.
Cuthbertson, Charles +2 more
openaire +5 more sources
An accurate model for genetic hitch-hiking
We suggest a simple deterministic approximation for the growth of the favoured-allele frequency during a selective sweep. Using this approximation we introduce an accurate model for genetic hitch-hiking.
Eriksson, A. +3 more
core +3 more sources
IAMBEE : a web-service for the identification of adaptive pathways from parallel evolved clonal populations [PDF]
IAMBEE is a web server designed for the Identification of Adaptive Mutations in Bacterial Evolution Experiments (IAMBEE). Input data consist of genotype information obtained from independently evolved clonal populations or strains that show the same ...
De Maeyer, Dries +6 more
core +1 more source
Effects of Linked Selective Sweeps on Demographic Inference and Model Selection [PDF]
Abstract The availability of large-scale population genomic sequence data has resulted in an explosion in efforts to infer the demographic histories of natural populations across a broad range of organisms. As demographic events alter coalescent genealogies, they leave detectable signatures in patterns of genetic variation within and ...
Schrider, Daniel R. +2 more
openaire +2 more sources
Evidence for sweep signatures in antibiotic-resistant strains in three species of bacteria [PDF]
Over the last decades antibiotic resistance has evolved and spread in many different bacterial species. From an evolutionary perspective, drug resistance is an adaptation to a new environment.
Anjani Pradhananga +4 more
doaj +2 more sources
The clarifying role of time series data in the population genetics of HIV.
HIV can evolve remarkably quickly in response to antiretroviral therapies and the immune system. This evolution stymies treatment effectiveness and prevents the development of an HIV vaccine.
Alison F Feder +2 more
doaj +1 more source

