Results 61 to 70 of about 123,629 (291)
SWEEPFINDER2: Increased sensitivity, robustness, and flexibility
, 2015 SweepFinder is a popular program that implements a powerful likelihood-based method for detecting recent positive selection, or selective sweeps. Here, we present SweepFinder2, an extension of SweepFinder with increased sensitivity and robustness to the ...
DeGiorgio, Michael +4 more
core +1 more source
Pervasive selective sweeps across human gut microbiomes
, 2023 AbstractThe human gut microbiome is composed of a highly diverse consortia of species which are continually evolving within and across hosts. The ability to identify adaptations common to many human gut microbiomes would not only reveal shared selection pressures across hosts, but also key drivers of functional differentiation of the microbiome that ...
Wolff, Richard, Garud, Nandita R.
openaire +2 more sources
A Selective Sweep across Species Boundaries in Drosophila [PDF]
Molecular Biology and Evolution, 2013 Adaptive mutations that accumulate during species divergence are likely to contribute to reproductive incompatibilities and hinder gene flow; however, there may also be a class of mutations that are generally advantageous and can spread across species boundaries.
Brand, Cara L. +3 more
openaire +3 more sources
Rapid adaptation of a polygenic trait after a sudden environmental shift
, 2017 Although a number of studies have shown that natural and laboratory populations initially well-adapted to their environment can evolve rapidly when conditions suddenly change, the dynamics of rapid adaptation are not well understood.
Jain, Kavita, Stephan, Wolfgang
core +1 more source
Traveling waves of selective sweeps
The Annals of Applied Probability, 2011 Published in at http://dx.doi.org/10.1214/10-AAP721 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Durrett, Rick, Mayberry, John
openaire +4 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Selective Sweeps in Multilocus Models of Quantitative Traits [PDF]
Genetics, 2012 Abstract We study the trajectory of an allele that affects a polygenic trait selected toward a phenotypic optimum. Furthermore, conditioning on this trajectory we analyze the effect of the selected mutation on linked neutral variation. We examine the well-characterized two-locus two-allele model but we also provide results for diallelic ...
Pavlos, Pavlidis +2 more
openaire +2 more sources
Advanced Engineering Materials, Volume 27, Issue 6, March 2025.The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez +5 more
wiley +1 more source
Allele Frequency Distribution Under Recurrent Selective Sweeps [PDF]
Genetics, 2006 Abstract The allele frequency of a neutral variant in a population is pushed either upward or downward by directional selection on a linked beneficial mutation (“selective sweeps”). DNA sequences sampled after the fixation of the beneficial allele thus contain an excess of rare neutral alleles.
openaire +2 more sources
Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolution Genome evolution and evolutionary systems biology [PDF]
, 2014 © 2014 Janha et al.; licensee BioMed Central Ltd.Background: Cytochrome P450 CYP2C19 metabolizes a wide range of pharmacologically active substances and a relatively small number of naturally occurring environmental toxins.
Janha, RE +5 more
core +3 more sources