Results 81 to 90 of about 16,978 (246)
Uncovering the architecture of selection in two Bos taurus cattle breeds
Evolutionary ApplicationsDirectional selection alters the genome via hard sweeps, soft sweeps, and polygenic selection. However, mapping polygenic selection is difficult because it does not leave clear signatures on the genome like a selective sweep.
Troy N. Rowan +2 more
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Adaptation in structured populations and fuzzy boundaries between hard and soft sweeps.
PLoS Computational Biology, 2019 Selective sweeps, the genetic footprint of positive selection, have been extensively studied in the past decades, with dozens of methods developed to identify swept regions.
Yichen Zheng, Thomas Wiehe
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Efficient Processing of Ranked Queries with Sweeping Selection [PDF]
, 2005 Existing methods for top-k ranked query employ techniques including sorting, updating thresholds and materializing views. In this paper, we propose two novel index-based techniques for top-k ranked query: (1) indexing the layered skyline, and (2) indexing microclusters of objects into a grid structure.
Wen Jin, Martin Ester, Jiawei Han 0001
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Advanced Functional Materials, EarlyView.Optoelectronic synaptic devices based on solution‐processed molecular telluride GST‐225 phase‐change inks are demonstrated for three‐factor learning. A global optical signal broadcast through a silicon waveguide induces non‐volatile conductance updates exclusively in locally electrically flagged memristors.
Kevin Portner +14 more
wiley +1 more source
Classic selective sweeps revealed by massive sequencing in cattle.
PLoS Genetics, 2014 Human driven selection during domestication and subsequent breed formation has likely left detectable signatures within the genome of modern cattle. The elucidation of these signatures of selection is of interest from the perspective of evolutionary ...
Saber Qanbari +7 more
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The Structure of Linkage Disequilibrium Around a Selective Sweep [PDF]
Genetics, 2007 Abstract The fixation of advantageous mutations by natural selection has a profound impact on patterns of linked neutral variation. While it has long been appreciated that such selective sweeps influence the frequency spectrum of nearby polymorphism, it has only recently become clear that they also have dramatic effects on local linkage ...
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Selective sweep probabilities in spatially expanding populations
, 2023 Abstract Evolution during range expansions shapes biological systems from microbial communities and tumours up to invasive species. A fundamental question is whether, when a beneficial mutation arises during a range expansion, it will evade clonal interference and sweep through the population to fixation.
Alexander Stein +3 more
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Advanced Functional Materials, EarlyView.A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
Allelic gene conversion softens selective sweeps
, 2023 Abstract The prominence of positive selection, in which beneficial mutations are favored by natural selection and rapidly increase in frequency, is a subject of intense debate. Positive selection can result in selective sweeps, in which the haplotype(s) bearing the adaptive allele “sweep” through the population ...
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Titanium Suboxides Responsible for Electronic Anomaly Near Room Temperature in the Ti3C2Tx MXene
Advanced Functional Materials, EarlyView.Our multi‐technique study reveals that the near‐room‐temperature anomaly in Ti3C2Tx MXene is linked to titanium suboxide nanodomains, including Ti3O5, embedded within the MXene host. Their temperature‐driven transformation provides an alternative explanation to solvent‐ and swelling‐based models and offers new insight into the thermally activated ...
Bence G. Márkus +8 more
wiley +1 more source