Results 151 to 160 of about 6,326,915 (384)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Adsorption behaviour of molecularly imprinted-beta-cyclodextrin polymers prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization for selective recognition of benzylparaben [PDF]
, 2015 Molecularly imprinted polymers (MIPs) are kinds of powerful materials with promising selective molecule recognition abilities. However, the conventional MIPs have relatively low binding capacity.
Asman, Saliza
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Discover MoleculesThe rapid and selective detection of nitroaromatic explosives such as 2,4-dinitrotoluene (2,4-DNT) remains a persistent analytical challenge. In this study, we report a novel sulfonyl chloride–substituted oxacalixarene (DCOC) that exhibits enhanced ...
Himali Upadhyay +9 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019 The definition technique of dispersion parameters of broadband matching and the frequency-selective chains based on use of wave properties of loading and demanded function of transfer is presented.
A. A. Svirydzenka
doaj
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Selective Transfer of Light-Emitting Diodes onto a Flexible Substrate via Laser Lissajous Scanning. [PDF]
ACS Omega, 2020 Jung D +5 more
europepmc +1 more source