Results 161 to 170 of about 6,326,915 (384)

Optimization of selective inversion recovery magnetization transfer imaging for macromolecular content mapping in the human brain

, 2018
Richard Dortch, Francesca Bagnato, Daniel F. Gochberg, John C. Gore, Seth A. Smith   +4 more
openalex   +2 more sources

Like What You Like: Knowledge Distill via Neuron Selectivity Transfer [PDF]

, 2017
Zehao Huang, Naiyan Wang
openalex   +1 more source

Data Selection for Transfer Unlearning

As deep learning models are becoming larger and data-hungrier, there are growing ethical, legal and technical concerns over use of data: in practice, agreements on data use may change over time, rendering previously-used training data impermissible for training purposes.
Sepahvand, Nazanin Mohammadi, Dumoulin, Vincent, Triantafillou, Eleni, Dziugaite, Gintare Karolina   +3 more
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Iron Pyrite Nanocrystals: A Potential Catalyst for Selective Transfer Hydrogenation of Functionalized Nitroarenes. [PDF]

ACS Omega, 2020
Adhikari M, Singh A, Echeverria E, McIlroy DN, Vasquez Y.   +4 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The study of Cerebral MRA with SORS-STC(Slice-Selective Off-Resonance Sinc Pulse-Satulation Transfer Contrast

, 1995
Koji Nonoshita, Ken Hoshino, Akira Arima
openalex   +2 more sources

Photochemical Electron and Hydrogen Transfer in Organic Synthesis: The Control of Selectivity [PDF]

, 2016
Norbert Hoffmann
openalex   +1 more source

Anion exchange membranes for electrochemical oxidation-reduction energy storage system [PDF]

Oxidation-reduction couples in concentrated solutions separated by appropriate ion selective membranes were considered as an attractive approach to bulk electrical energy storage. A key problem is the development of the membrane.
Gahn, R. F., Odonnell, P. M., Sheibley, D. W.   +2 more
core   +1 more source