Results 31 to 40 of about 125,114 (199)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Interface between Nanoenergy and Self-Powered Electronics

open access: yesSensors, 2021
In recent decades, nanogenerators based on several techniques such as triboelectric effects, piezoelectric effects, or other mechanisms have experienced great developments. The nanoenergy generated by nanogenerators is supposed to be used to overcome the
Yi-Lin Wang   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Self‐Powered Stretchable Mechanoluminescent Optical Fiber Strain Sensor

open access: yesAdvanced Intelligent Systems, 2021
Strain sensors that can work sustainably and continuously without any external power supply are highly desirable for future wearable and implantable devices.
Haohua Liang   +10 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Portable and wearable self-powered systems based on emerging energy harvesting technology

open access: yesMicrosystems & Nanoengineering, 2021
A self-powered system based on energy harvesting technology can be a potential candidate for solving the problem of supplying power to electronic devices.
Chen Xu   +3 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Recent Progress on Built-in Wave Energy Converters: A Review

open access: yesJournal of Marine Science and Engineering
A built-in wave energy converter (BI-WEC) is a type of WEC that is fully encapsulated within a floating body that is easy to integrate and promotes reliability.
Hao Wang   +5 more
doaj   +1 more source

Nanogenerator-based self-powered sensors for data collection

open access: yesBeilstein Journal of Nanotechnology, 2021
Self-powered sensors can provide energy and environmental data for applications regarding the Internet of Things, big data, and artificial intelligence.
Yicheng Shao   +5 more
doaj   +1 more source

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