Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger +5 more
wiley +1 more source
A novel nonlinear infrasound sensor concept based on a free‐standing ion conductive gel membrane is introduced. Acoustic signals are directly transduced into an electrical signal using an internal application mechanisms (gating). The nonlinearity might be used for neuromorphic in‐sensor computing. ABSTRACT Measuring low‐frequency or infrasound acoustic
Maarten Mittmann +6 more
wiley +1 more source
The Contribution of the Self-adjusting File in Debris Removal in Root Canal Retreatment: A Systematic Review and Meta-analysis of <i>in Vitro</i> Studies. [PDF]
El Abbassi S, Sakout M.
europepmc +1 more source
Comparative evaluation of apically extruded debris with V-Taper, ProTaper Next, and the Self-adjusting File systems. [PDF]
Vyavahare NK, Raghavendra SS, Desai NN.
europepmc +1 more source
NeuroVisio SyncPatch integrates skin‐conformal electromyography (EMG) electrodes with camera‐tracked markers to jointly assess muscle activity and three‐dimensional knee kinematics during rehabilitation. Parallel feedback pathways provide real‐time kinematic guidance during movement and post‐trial neuromuscular feedback.
Bohyung Choi +11 more
wiley +1 more source
Evaluation of the incidence of microcracks caused by Mtwo and ProTaper Next rotary file systems versus the self-adjusting file: A scanning electron microscopic study. [PDF]
Saha SG +5 more
europepmc +1 more source
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko +7 more
wiley +1 more source
Comparison of the incidence of postoperative pain after using a continuous rotary system, a reciprocating system, and a Self-Adjusting File system in single-visit endodontics: A prospective randomized clinical trial. [PDF]
Saha SG +5 more
europepmc +1 more source
document are those of the author and should not be interpreted as representing the official policies, either expressed or implied, of any sponsoring institution, the U.S. government or any other entity.
Daniel Dominic +2 more
core
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang +4 more
wiley +1 more source

