Results 111 to 120 of about 240,671 (273)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Do children have insights into their performance in an inhibitory control task?: An explorative study with 9- and 11-year-olds

Acta Psychologica
Accurate self-evaluation of one's performance is a key metacognitive skill that supports self-regulated learning and academic success, yet it develops gradually throughout childhood. This study examined the performance and self-evaluations of performance
Ebru Ger, Elena Cravet
doaj   +1 more source

Level of Social Appearance Anxiety in Individuals with and without Alignment of Teeth

Turkish Journal of Orthodontics, 2017
Objective:The aim of this study is to determine the level of social appearance anxiety in individuals with and without alignment of teeth and to demonstrate that orthodontic treatment is effective in reintegrating the individual into society, as well as ...
Mihri Amasyalı, Fidan Alakuş Sabuncuoğlu   +1 more
doaj   +1 more source

The Mediating Role of Self-Goal Alignment in the Relationship between Academic Achievement and Psychological Capital in Students [PDF]

پژوهش در روش‌های آموزش
The purpose of the present study was to investigate the mediating role of self-goal alignment in the relationship between academic achievement and psychological capital in students. The research method was a descriptive correlational study.
Forough Farzan Mehr, Jafar Bahadori Khosroshahi   +1 more
doaj   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

A Coarse Alignment Algorithm Based on Vector Reconstruction via Sage–Husa AKF for SINS on a Swaying Base

Sensors
As a rapid self-alignment method, the coarse alignment technique, under swaying-base conditions, can enhance initial attitude determination speed without external aids, which is critical for strapdown inertial navigation systems (SINSs).
Yongyun Zhu, Bingbo Cui, Dianlei Han, Yaohui Zhu, Yuanyuan Gao, Shede Liu   +5 more
doaj   +1 more source

Realization of Three-Dimensionally MEMS Stacked Comb Structures for Microactuators Using Low-Temperature Multi-Wafer Bonding with Self-Alignment Techniques in CMOS-Compatible Processes. [PDF]

Micromachines (Basel), 2021
Teo AJT, Li KHH.
europepmc   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source