Results 91 to 100 of about 5,333,670 (270)

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

Body image self-blame

, 2011
This study examines the relation between adolescent depression, shame/characterological self-blame, and body image. It addresses the question: Do adolescents’ attributions and feelings about their body image make them more prone to depression?
Kumar, Ekta
core  

Enhanced Acoustic Adhesion Enabling Agile and Small Wall‐Climbing Robot Design With Anisotropic Origami Structure

Advanced Science, EarlyView.
This 28 g robot incorporates innovative ring structures and anisotropic origami springs to achieve high speeds and exceptional load capacity. It successfully carries a 100 g payload while ascending walls or ceilings at speeds of up to 8 and 20 cm/s, demonstrating enhanced adhesion and maneuverability over current climbing robots.
Xinxian Chen, Kanglong Yuan, Ao Qin, Yikun Liu, Yusen Ma, Jun Peng   +5 more
wiley   +1 more source

Re‐Thinking Electronic Circuit Design Through Emerging Reconfigurable Field Effect Transistors

Advanced Science, EarlyView.
Graphical illustration of reconfigurable field effect transistor (RFET) operation modes, including n‐type, p‐type, and ambipolar transport, as well as their areas of application discussed in this review: digital circuit design, analog circuit design, post‐Shannon computing, and sensing. ABSTRACT Reconfigurable field‐effect transistors, short RFETs, are
Jens Trommer, Juan P. Martinez, Yuxuan He, Giulio Galderisi, Katrin Pingen, Eduardo Sergio Oliveros‐Mata, Lisa Tellis, Cigdem Cakirlar, Christoph Beyer, Brojogopal Sapui, Joachim Knoch, Klaus Hofmann, Sandro Carrara, Eugenio Cantatore, Max C. Lemme, Ian O'Connor, Akash Kumar, Andre Heinzig, Thomas Mikolajick, Walter M. Weber   +19 more
wiley   +1 more source

Symbolic self-translation in Bloke Modisane's Blame Me on History

Tydskrif vir Letterkunde, 2017
The article examines Modisane's self-portrayal in his autobiography, Blame Me on History (1963). The author argues that for Modisane autobiographical self-representation takes the form of a complex and multi-layered process of symbolic and metaphorical ...
Thengani Ngwenya
doaj   +1 more source

Field Emission Enhancement in Graphene/Cu Cathodes Through Laser‐Shock‐Induced Modulation of Geometry and Work Function

Advanced Science, EarlyView.
Laser shock microforming converts graphene/Cu foils into flexible cathodes without transfer while modulating their local work function. Lower barriers near protrusion tops and rims coincide with electric field concentration, favoring electron emission.
Ximei Xu, Haonan Tao, Wenming Li, Xuyin Li, Jiacong Lin, Mingyang Yang, Ming Zhou   +6 more
wiley   +1 more source

Behavioral Self-Blame in PTSD-Etiology, Risk Factors, and Proposed Interventions. [PDF]

Int J Environ Res Public Health, 2023
Raz A, Rubinstein R, Shadach E, Chaikin G, Ben Yehuda A, Tatsa-Laur L, Kedem R, Shelef L.   +7 more
europepmc   +1 more source

From Artificial to Embodied and Physical Intelligence in Smart Manufacturing

Advanced Science, EarlyView.
Smart manufacturing is reframed through complementary artificial, embodied, and physical intelligence, spanning computational reasoning, perception‐action coupling, and material‐level adaptation. Their integration across design, fabrication, operation, and maintenance reveals how intelligence can be co‐designed across algorithms, embodied agents, and ...
Kang Wang, Xinyu Lu, Tong Liu, Jinjie Fang, Xin Li, Siqian Wu, Liuchao Jin, Wei‐Hsin Liao, Shuyou Zhang, Jianrong Tan   +9 more
wiley   +1 more source

Advances in Josephson Junction Materials and Processes Toward Practical Quantum Computing

Advanced Science, EarlyView.
Emerging materials for quantum computing, including crystalline materials, two‐dimensional van der Waals materials, two‐dimensional electron gas systems, ferromagnets, and unconventional (e.g., d‐wave) superconductors, offer opportunities to engineer next‐generation Josephson junctions.
Hyunseong Kim, Gyunghyun Jang, Seungwon Jin, Jaewon An, Dongbin Shin, Hyeon‐Jin Shin, Jie Luo, Akel Hashim, Irfan Siddiqi, Yosep Kim, Long B. Nguyen, Hoon Hahn Yoon   +11 more
wiley   +1 more source

Atomic‐Scale Mechanisms of Anisotropic Thermal Decomposition in GeSn Alloys With Stepwise Pinning

Advanced Electronic Materials, EarlyView.
Combining in situ TEM with DFT calculations, this work elucidates atomic‐scale anisotropic thermal decomposition in GeSn films, identifying laminar receding in defect‐free regions and stepwise pinning at stacking faults. Driven by crystallographic anisotropy and defect‐mediated energetic penalties, these findings establish a physical framework for ...
YiXin Wang, Qi Liu, XiYan Chang, Chi Xu, Tao Wang, XinZheng Li, ChunLai Xue   +6 more
wiley   +1 more source