Results 51 to 60 of about 4,822,574 (285)

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec   +5 more
wiley   +1 more source

Les usages de l’alcool à Meknès (Maroc) : entre interdits, censure et autocensure

open access: yesL’Année du Maghreb, 2020
In Morocco, alcohol is forbidden to Muslims, and yet many shops (bars, grocery stores...) offer these goods to consumers who are Muslims. In order to be able to sell alcohol, shopkeepers organize, on the one hand, according to their own arrangements ...
Philippe Chaudat
doaj   +1 more source

Foundation Model‐Enabled Multimodal Deep Learning for Prognostic Prediction in Colorectal Cancer with Incomplete Modalities: A Multi‐Institutional Retrospective Study

open access: yesAdvanced Science, EarlyView.
FLARE, a multimodal AI framework, combines pathology slides, radiology scans, and clinical reports to predict colorectal cancer outcomes, even when some tests are missing. Evaluated retrospectively in 1679 patients from four medical centers, it consistently achieved the best prognostic accuracy and clearly separated high‐ and low‐risk groups.
Linhao Qu   +6 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

The Eye of the Censor: A Critical Genealogy of Censorship as Transparency (16th-18th Centuries)

open access: yesRevue LISA, 2013
The paper uses a critical and genealogical approach in order to clarify and define the notion of censorship. It aims at providing insight into the pragmatic conditions of enunciation under which various models of power and governmentality created and ...
Magali Bessone
doaj   +1 more source

How Does Cultural and Colonial Heritage Affect Optimal Branding Strategies? Evidence From the Rice Sector in Senegal

open access: yesAgribusiness, EarlyView.
ABSTRACT Africa's cultural and colonial heritage has profoundly segmented rice markets. Whereas in ancient centers of rice domestication, consumers maintained preferences for local rice consistent with their cultural heritage, preferences have shifted toward imported Asian rice in coastal areas around seaports, due to prior exposure to colonial import ...
Kofi Britwum, Matty Demont
wiley   +1 more source

Self-censorship: the most insidious gag

open access: yesPacific Journalism Review, 1995
Journalists feel the pressures to conform to the accepted values of their workplace. But those values come not just from editors and producers above them, but significantly from the journalists' peers—their fellow journalists.
Peter Cronau
doaj   +1 more source

Consumers' Willingness to Pay a Premium for Climate‐Friendly Food Production: The Role of Production Method Information and Social Norms

open access: yesAgribusiness, EarlyView.
ABSTRACT This study examines whether information about production methods and social norms can increase consumers' willingness to pay (WTP) a price premium for food produced using climate‐friendly farming methods. A randomized survey experiment was conducted with 1568 respondents across Denmark, Lithuania, and Spain, who were assigned to one of four ...
Kassa Tarekegn Erekalo   +5 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

open access: yesThe Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth   +10 more
wiley   +1 more source

Factors Affecting Self-Censorship Among Polish Journalists

open access: yesZeszyty Prasoznawcze, 2021
The aim of this paper is to recognize the factors limiting journalists’ sense of autonomy and affecting the level of their self-censorship during the last three decades of the post-transformation ...
Agnieszka Stępińska
doaj   +1 more source

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