Results 61 to 70 of about 346,363 (261)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Origin and reasons of synergy establishment [PDF]
, 2015 In modern science there are several definitions of synergy as a science of self-organization. Well-known scientist I. Pryhozhyn, one of the founders of synergistic research, believes that this science should be defined as “theory of dissipative ...
Yakimtsov, V.V.
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Local and the Global: Hokusai's Great Wave in Contemporary Product Design [PDF]
, 2012 This article examines the impact and significance of Hokusai’s so-called The Great Wave in contemporary product promotion and design. Arguably Japan’s first global brand, this influential 19th-century woodcut has been widely adopted to style and ...
Guth, Christine
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Meeting the Stranger: Closing the Distance in Ernest Hemingway’s \u3ci\u3eA Moveable Feast\u3c/i\u3e [PDF]
, 2019 This thesis provides an in-depth analysis of Ernest Hemingway’s memoir, A Moveable Feast. The analysis focuses on how AMF functions as a memoir, given its complicated publication history.
Raszinski, Brett Joseph
core +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Parador y mirador: Pinohuacho, Chile
ARQ, 2010 Este proyecto de título, construido gracias a la participación de lugareños y el reciclaje de material abandonado, propone un espacio de contemplación de un paisaje previamente explotado. Los volúmenes generados se disponen y entregan gratuitamente en el
Rodrigo Sheward
doaj
EnergiesThe impacts of renovation actions on pre- and post-retrofitting building performances are complex to analyse, particularly small and potentially self-actuated actions, such as adding insulation layers to a cold roof slab or changing doors.
Giacomo Chiesa, Paolo Carrisi
doaj +1 more source
Communications, 2020 The main aim of the paper is the analysis of simulation model reflecting selected in-warehouse logistics processes in the aspect of their availability.
Mariusz Kostrzewski +3 more
doaj +1 more source