Results 81 to 90 of about 493,324 (353)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Self-consumption of electricity from renewable sources

open access: yes, 2015
If the cost of energy production from renewable energy sources (RES) reduces below the level of electricity retail prices, self-consumption (SC) can contribute to market integration of RES. Support schemes such as feed-in tariffs could be phased out in view of parity of retail prices and RES production costs. In combination with electricity storage and
Dehler, J.   +7 more
openaire   +1 more source

Participatory Data Analysis: A New Method for Investigating Human Energy Practices [PDF]

open access: yes, 2014
This paper presents a novel data-driven method to investigate the interdependence between technology design and human energy practices. The method – called Participatory Data – makes use of fine-grained energy data collected via smart meters and smart ...
Bourgeois, Jacky   +3 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Improvement in Energy Self-Sufficiency in Residential Buildings Using Photovoltaic Thermal Plants, Heat Pumps, and Electrical and Thermal Storage

open access: yesEnergies
Promoting complete decarbonization by entrusting the energy supply through renewable sources (wind, photovoltaic, solar thermal, etc.) is one of the key strategies in the building sector.
Antonio Gagliano   +2 more
doaj   +1 more source

"Plantar pro gasto": a importância do autoconsumo entre famílias de agricultores do Rio Grande do Sul

open access: yesRevista de Economia e Sociologia Rural, 2008
O artigo discute a valoração e importância da produção para o autoconsumo na reprodução social das unidades familiares e caracteriza os alimentos autoconsumidos.
Catia Grisa, Sergio Schneider
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

How real are Macroeconomic Parameters of Romania during 1989-2009 [PDF]

open access: yes
The main idea of this article is that GDP of Romania related to the last 12 years is extremely high and creates the illusion that in a short period of time it could become a developed country from economic viewpoint.
Angelica BACESCU - CARBUNARU
core  

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Fault Diagnosis for Photovoltaic Systems: A Validated Industrial SCADA Framework

open access: yesApplied Sciences
Standard monitoring for photovoltaic (PV) systems, often based on IEC 61724-1, the standard published by the International Electrotechnical Commission (IEC) titled “Photovoltaic system performance—Part 1: Monitoring”, is frequently slow to detect ...
Anastasiia Snytko   +3 more
doaj   +1 more source

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