Results 131 to 140 of about 75,871 (297)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
The Effects of Self-Criticism and Self-Compassion on Adolescents' Depressive Symptoms and Nonsuicidal Self-Injury. [PDF]
Psychol Res Behav Manag, 2023 Gao Y, Liu X, Liu J, Wang H.
europepmc +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Recollections of Parental Rejection, Self-Criticism and Depression in Suicidality [PDF]
, 2013 The present study examines whether self-criticism and depressive symptoms mediate the relationship between recollections of parental rejection and suicidality.
Blatt, Sidney +2 more
core
A review of client self-criticism in psychotherapy
, 2013 Research on the construct of self-criticism has been gaining attention in the psychopathology and psychotherapy literature. The aims of this review are to provide an integrated theoretical and empirical understanding of client self-criticism and its ...
Kannan, Divya, Levitt, Heidi
core +1 more source
Addressing self-criticism in depression using CBT-based emotion-focused chairwork: study protocol of a randomised controlled trial. [PDF]
BMJ Open, 2023 Kroener J, Mahler J, Sosic-Vasic Z.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Effect of compassion-focused therapy on self-criticism and self-soothing: A meta-analysis. [PDF]
Br J Clin Psychol, 2023 Vidal J, Soldevilla JM.
europepmc +1 more source