Results 41 to 50 of about 69,781 (255)

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Criticism and Self-criticism: participatory evaluation in rural schools

Educação: Teoria e Prática, 2010
This paper approaches some possibilities implementation of participatory evaluation,which is seen as an important dimension of the accomplished pedagogical work inrural schools organized according to politician-pedagogical principles of the movementof ...
Ilma Ferreira Machado
doaj  

Guiding Clients Towards Self-Kindness and Acceptance: Wrestling With the Inner Critic

Psychotherapy and Counselling Journal of Australia
Research and methodology on the treatment of self-criticism in counselling is limited in the recent literature. This article describes how harsh automatic self-criticism became viewed within several theoretical frameworks as a sub-personality with a ...
Mark Pearson, Helen Wilson
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

New instability and symmetry: criticism and Neobaroque’s self-criticism

Gragoatá, 2006
This essay proposes an interpretation of the neobaroque from the perspective of the work of its main poet-thinkers: the Brazilian Haroldo de Campos, the French-Cuban Severo Sarduy and the Argentinean Arturo Carrera. Aiming at providing a criticism of the
Joca Wolff
doaj  

Embodying compassion: a virtual reality paradigm for overcoming excessive self-criticism. [PDF]

PLoS ONE, 2014
Virtual reality has been successfully used to study and treat psychological disorders such as phobias and posttraumatic stress disorder but has rarely been applied to clinically-relevant emotions other than fear and anxiety.
Caroline J Falconer, Mel Slater, Aitor Rovira, John A King, Paul Gilbert, Angus Antley, Chris R Brewin   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The self-criticism of science [PDF]

SSRN Electronic Journal, 2013
The neoteric human being is now being cut off from the order of nature and establishes itself as the rationally reflecting and acting subject which is now posited against the object of its cognitive and practical activity. Civilization is constituted as the product of human activity, as an artifact and technical construct.
openaire   +1 more source