Results 221 to 230 of about 14,848 (289)

Few-shot cross-episode adaptive memory for metal surface defect semantic segmentation. [PDF]

Sci Rep
Zhang J, Ding H, Peng M, Tu S, Chen G, Liu Y.   +5 more
europepmc   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

A lightweight transformer-based hybrid encoder-decoder model for chest X-ray medical report generation. [PDF]

Sci Rep
Ucan M, Kaya B, Kaya M, Alhajj R.
europepmc   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Future-aware blood glucose forecasting using knowledge distillation with transformer-based sequence-to-sequence models. [PDF]

Sci Rep
Sun X, Li H, Yu X.
europepmc   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

Advanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao, Mei Li, Mengjiao Fan, Chuanhuan Liu, Jie Jiang, Jia Song, Yingzhu Liu   +6 more
wiley   +1 more source

Automated Detection of Lacunes in Brain MR Images Using SAM with Robust Prompts via Self-Distillation and Anatomy-Informed Priors

Deepika P, Shanker G, Narayanan R, Sundaresan V.   +3 more
europepmc   +1 more source

LDFSAM: Localization Distillation-Enhanced Feature Prompting SAM for Medical Image Segmentation. [PDF]

J Imaging
Zhao X, Wang C, Xu H, Zhou H, Yu Z, Chen T, Wei X, Zhang R.   +7 more
europepmc   +1 more source

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

Advanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García, José A. Pineda‐Pardo, Inés Trigo‐Damas, Marta Gutiérrez, Marta Castillo‐Ortiz, Megan Carrillo, Alejandro Reinares‐Sebastian, Víctor Medina‐Chavarrías, Itay Rachmilevitch, Masahiko Takada, José A. Obeso, Javier Blesa   +11 more
wiley   +1 more source

Privacy-Aware Continual Self-Supervised Learning on Multi-Window Chest Computed Tomography for Domain-Shift Robustness. [PDF]

Bioengineering (Basel)
Tasai R, Li G, Togo R, Ogawa T, Hirata K, Tang M, Yoshimura T, Sugimori H, Nishioka N, Shimizu Y, Kudo K, Haseyama M.   +11 more
europepmc   +1 more source