Results 41 to 50 of about 6,858,976 (254)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Matrix-Product Codes over Commutative Rings and Constructions Arising from σ,δ-Codes
A well-known lower bound (over finite fields and some special finite commutative rings) on the Hamming distance of a matrix-product code (MPC) is shown to remain valid over any commutative ring R.
Mhammed Boulagouaz, Abdulaziz Deajim
doaj +1 more source
Quantum dialogue protocol based on self-dual quantum low density parity check codes
In quantum channels, particles are usually affected by noise during transmission. A quantum dialogue protocol based on self-dual quantum low density parity check codes was proposed to resist noise attacks.
LIU Fen, XU Pengao +1 more
doaj +3 more sources
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
On Reversibility and Self-Duality for Some Classes of Quasi-Cyclic Codes
In this work, we study two classes of quasi-cyclic (QC) codes and examine how several properties can be combined into the codes of these classes. We start with the class of QC codes generated by diagonal generator polynomial matrices; a QC code in this ...
Ramy Taki Eldin, Hajime Matsui
doaj +1 more source
Infinite Dimensional Symmetries of Self-Dual Yang-Mills Theories. [PDF]
We construct infinite dimensional symmetries of the Chalmers-Siegel action describing the self-dual sector of non-supersymmetric Yang-Mills. The symmetries are derived by virtue of a canonical transformation between the Yang-Mills fields and new fields ...
WARDLOW, ADAM,BARTHOLOMEW +1 more
core
Optimal ternary formally self-dual codes [PDF]
In this paper, we study ternary optimal formally self-dual codes. Bounds for the highest minimum weight are given for length up to 30 and examples of optimal formally self-dual codes are constructed.
Steven T. Dougherty +5 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source

