Results 111 to 120 of about 77,350 (261)

Understanding Self-Government

open access: yesJournal of Autonomy and Security Studies
Increasingly the go-to option for managing separatism, territorial autonomy provides special self-government for territorially concentrated minorities. Rather than an institution in its own right, autonomy is often studied as a form of decentralization and federalism or an endpoint in peace processes.
Barter, Shane, Barter, Shane
openaire   +2 more sources

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

Educational Implications of Self-Governance Concept in Teachings of Imam Ali (AS): Improving Social Wellbeing and Validating It [PDF]

open access: yesIranian Journal of Educational Research
Objective: This research endeavors to elucidate the educational implications of the self-management paradigm as delineated in the teachings of Imam Ali (AS), particularly in relation to enhancing social wellbeing and its subsequent validation.
Najmeh Khalili   +2 more
doaj  

SELF-GOVERNANCE AS A CORRELATE OF DEMOCRACY

open access: yesPolitology bulletin
The article provides a systematic analysis of the concept of self-governance in the context of contemporary democratic theory. It identifies the features of democratic self-governance and examines related theories, including localism, decentralization of power, political autonomy, and the principle of subsidiarity.
openaire   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

INSTRUMENTS OF DEVELOPMENT OF SELF-GOVERNMENT IN THE PROCESS FOCUSED ORGANIZATION

open access: yesВестник университета, 2017
In the article a methodology of vertical management by objective and horizontal development mechanism combination is offered in the form of PDCA and DMAIC cycles kinematic pair. Author suggests to join these cycles in the A phase as a result of deviation
A. Dolgaya
doaj  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

INSTRUMENTS OF DEVELOPMENT OF SELF-GOVERNMENT IN THE PROCESS FOCUSED ORGANIZATION

open access: yesВестник университета, 2019
In the article a methodology of vertical management by objective and horizontal development mechanism combination is offered in the form of PDCA and DMAIC cycles kinematic pair. Author suggests to join these cycles in the A phase as a result of deviation
A. Dolgaya
doaj  

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