β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Impact of children's self-harm on caregivers' mental health and family functioning. [PDF]
Ortin-Peralta A +4 more
europepmc +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
Mental health treatment experiences and barriers and facilitators to treatment among sexual and gender minoritized adolescents at risk for self-harm. [PDF]
Bhoja A +9 more
europepmc +1 more source
Time‐Dependent Oxidation and Scale Evolution of a Wrought Co/Ni‐Based Superalloy
This study shows how a new wrought Co/Ni‐based superalloy resists oxidation at 800 ∘$^\circ$C. The oxide scale changes from rough, fast‐growing spinel to a dense, protective chromia–alumina layer. Atom probe analysis reveals tiny refractory‐rich bubbles at the interface that mark the transition to long‐term, diffusion‐controlled protection ...
Cameron Crabb +6 more
wiley +1 more source
Correction: Treatment effects of psychological interventions on self‑harm in individuals with PTSD: a systematic review and meta‑analysis protocol. [PDF]
Tsang A +3 more
europepmc +1 more source
Prevalence, Risk Factors and Correlates of Deliberate Self-Harm Behaviors in Bangladesh: A Narrative Review of Cross-Sectional Studies (1995-2025). [PDF]
Rahman M +5 more
europepmc +1 more source
Do new labels solve old problems? Conceptual, ethical, and clinical challenges of constructing restrictive eating behaviours as "self-harm". [PDF]
Downs J +7 more
europepmc +1 more source

