Results 91 to 100 of about 5,645,164 (308)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Self-Adapting Hydrogel to Improve the Therapeutic Effect in Wound-Healing

open access: yes, 2018
Smart materials that can respond to multistimuli have been broadly studied. However, the smart materials that can spontaneously answer the ever-changing inner environment of living bodies have not been reported.
Yen Wei (1396648)   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Self‐Healing Hydrogels: Mechanisms and Biomedical Applications

open access: yesMedComm
Hydrogels have emerged as dependable candidates for tissue repair because of their exceptional biocompatibility and tunable mechanical properties. However, conventional hydrogels are vulnerable to damage owing to mechanical stress and environmental ...
Lingling Xue   +7 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Toughening Self‐Healing Elastomers with Chain Mobility

open access: yesAdvanced Science
Enhancing fracture toughness and self‐healing within soft elastomers is crucial to prolonging the operational lifetimes of soft devices. Herein, it is revealed that tuning the polymer chain mobilities of carboxylated‐functionalized polyurethane through ...
Matthew Wei Ming Tan   +5 more
doaj   +1 more source

Recent Advances of Self-Healing Materials for Civil Engineering: Models and Simulations

open access: yesBuildings
Empowering materials with self-healing capabilities is an attractive approach for sustainable development. This strategy involves using different methods to automatically heal microcracks and damages that occur during the service life of materials or ...
Cen-Ying Liao   +4 more
doaj   +1 more source

Self‐Healing Microsupercapacitors with Size‐Dependent 2D MXene

open access: yesChemElectroChem, 2020
Very recently, 2D MXene has attracted a lot of attention in energy storage, due to its large specific surface area, good hydrophilicity, good conductivity and adjustable composition.
Xingxing Li   +7 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Self-Healing Polymers From Principles to Applications

open access: yes, 2013
Self-healing is a well-known phenomenon in nature: a broken bone merges after some time and if skin is damaged, the wound will stop bleeding and heals again.
Binder, Wolfgang H.
core  

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