Results 131 to 140 of about 5,645,164 (308)

Healing for Our Stolen Generations: sharing our stories

, 2016
Executive summary This report is a review of the first two years of projects funded under the Healing Foundation’s Stolen Generations Initiative 2013-2015.
Healing Foundation
core  

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Self-healing electronic skin with high fracture strength and toughness

Nature Communications
Human skin is essential for perception, encompassing haptic, thermal, proprioceptive, and pain-sensing functions through ion movement. Additionally, it is mechanically resilient and self-healing for protection.
Jaehoon Jung, Sunwoo Lee, Hyunjun Kim, Wonbeom Lee, Jooyeun Chong, Insang You, Jiheong Kang   +6 more
doaj   +1 more source

Self-healing in leprosy: A systematic review

PLOS Neglected Tropical Diseases
Background Leprosy, caused by Mycobacterium leprae, affects multiple body systems and can lead to preventable disability if untreated. While multidrug therapy (MDT) has been available since 1982, historical evidence suggests that untreated leprosy can resolve spontaneously.
Sophie C. W. Stuetzle, Ann-Kristin Bonkass, Wim H. van Brakel, Anne Schoenmakers, Anil Fastenau   +4 more
openaire   +4 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Strength properties of self-healing mortars [PDF]

, 2014
Cementitious materials are the most widely used in building materials all over the world. However, deterioration is inevitable even since in the very beginning of the service life.
Husseien, Ghassan Fahim
core  

Recent advances in self-healing hydrogel composites for flexible wearable electronic devices

Nano Research Energy
Flexible electronic devices with mechanical properties like the soft tissues of human organs have great potential for the next generation of wearable and implantable electronic devices.
Xihan Tan, Kaibin Chu, Zhijie Chen, Ning Han, Xueliang Zhang, Hongwei Pan, Wei Guo, Guoxing Chen, Bing-Jie Ni, Zhenyu Zhou, Hui Song   +10 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source