Results 81 to 90 of about 4,950,937 (310)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Self‐Healing Ionogel‐Enabled Self‐Healing and Wide‐Temperature Flexible Zinc‐Air Batteries with Ultra‐Long Cycling Lives

open access: yesAdvanced Science
Hydrogel‐based zinc‐air batteries (ZABs) are promising flexible rechargeable batteries. However, the practical application of hydrogel‐based ZABs is limited by their short service life, narrow operating temperature range, and repair difficulty. Herein, a
Hongli Li   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Self‐healing Coatings Based on Epoxy Vitrimers

open access: yesMacromolecular Materials and Engineering
The present study focuses on the development of epoxy‐based vitrimeric coatings with thermal‐healing ability. For this purpose, ethylene glycol diglycidyl ether (EG) is crosslinked with methyl nadic anhydride (MNA) in the presence of 1‐methylimidazole (1‐
Angela Marotta   +4 more
doaj   +1 more source

Self-healing Tile Sets [PDF]

open access: yes, 2006
Biology provides the synthetic chemist with a tantalizing and frustrating challenge: to create complex objects, defined from the molecular scale up to meters, that construct themselves from elementary components, and perhaps even reproduce themselves. This is the challenge of bottom-up fabrication.
openaire   +3 more sources

Self-healing materials and multinozzle printheads with embedded microvascular networks [PDF]

open access: yes, 2011
Microvascular networks are pervasive in biological systems, assisting in the repair of tissue damage, regulation of temperature, and efficient distribution of nutrients.
Hansen, Christopher J.
core  

AUTOGENOUS SELF-HEALING OF POLYPROPYLENE FIBER REINFORCED ETTRINGITE-BASED COMPOSITE

open access: yes, 2022
This study intends to advance the poor knowledge on the ability of an ettringite-based binder to obtain autogenous self-healing and its relevant mechanism. We developed a high performance polypropylene fiber-reinforced cementitious composite based on the
Mirja Illikainen   +4 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Self-Healing Behaviors of Tough Polyampholyte Hydrogels [PDF]

open access: yes, 2016
Recently, polyampolytes have been discovered to form hydrogels that possess high toughness, full resilience, and self-healing between two cut surfaces. The self-healing of this class of hydrogels is based on the re-forming of the multiple ionic bonds at ...
Jian Ping Gong (1503811)   +26 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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