Results 61 to 70 of about 197,167 (266)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Advanced ScienceHydrogel‐based zinc‐air batteries (ZABs) are promising flexible rechargeable batteries. However, the practical application of hydrogel‐based ZABs is limited by their short service life, narrow operating temperature range, and repair difficulty. Herein, a
Hongli Li +3 more
doaj +1 more source
Mechanically Robust, Recyclable, and Self‐Healing Polyimine Networks
Advanced Science, 2023 To achieve energy saving and emission reduction goals, recyclable and healable thermoset materials are highly attractive. Polymer copolymerization has been proven to be a critical strategy for preparing high‐performance polymeric materials.
Ping Yu +10 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
, 2006 Biology provides the synthetic chemist with a tantalizing and frustrating challenge: to create complex objects, defined from the molecular scale up to meters, that construct themselves from elementary components, and perhaps even reproduce themselves. This is the challenge of bottom-up fabrication.
openaire +3 more sources
Self-healing catalysis in water [PDF]
Proceedings of the National Academy of Sciences, 2017 Significance Water provides an attractive medium for storing solar energy via water splitting. Charge-separated states generated by solar capture may be transferred to catalysts that split water to hydrogen and oxygen. Most water-splitting catalysts comprising earth-abundant elements are susceptible to corrosion when operated in ...
Cyrille Costentin, Daniel G. Nocera
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Self‐healing Coatings Based on Epoxy Vitrimers
Macromolecular Materials and EngineeringThe present study focuses on the development of epoxy‐based vitrimeric coatings with thermal‐healing ability. For this purpose, ethylene glycol diglycidyl ether (EG) is crosslinked with methyl nadic anhydride (MNA) in the presence of 1‐methylimidazole (1‐
Angela Marotta +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source