Results 51 to 60 of about 22,364 (259)

Regulation of inflammatory microenvironment using a self-healing hydrogel loaded with BM-MSCs for advanced wound healing in rat diabetic foot ulcers

Journal of Tissue Engineering, 2020
A diabetic foot ulcer (DFUs) is a state of prolonged chronic inflammation, which can result in amputation. Different from normal skin wounds, various commercially available dressings have not sufficiently improved the healing of DFUs.
Haotian Bai, Noh Kyu-Cheol, Zhonghan Wang, Yutao Cui, He Liu, Hou Liu, Yubin Feng, Yue Zhao, Quan Lin, Zuhao Li   +9 more
doaj   +1 more source

Multifunctional Extracellular Matrix Hydrogel with Self-Healing Properties and Promoting Angiogenesis as an Immunoregulation Platform for Diabetic Wound Healing

Gels, 2023
Treating chronic wounds is a global challenge. In diabetes mellitus cases, long-time and excess inflammatory responses at the injury site may delay the healing of intractable wounds.
Zhenghua Sun, Hao Xiong, Tengfei Lou, Weixuan Liu, Yi Xu, Shiyang Yu, Hui Wang, Wanjun Liu, Liang Yang, Chao Zhou, Cunyi Fan   +10 more
doaj   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Reconfigurable Magnetic Soft Microrobot for Acoustically Triggered Targeted Bacterial Sterilization

Advanced Functional Materials, EarlyView.
Reconfigurable magnetic soft microrobots integrate in situ‐grown piezoelectric zinc oxide nanorods that produce reactive oxygen species upon acoustic excitation. Combining magnetically guided transport with thermally induced planar reconfiguration, the microrobots achieve targeted delivery and enhanced bacterial sterilization through efficient on ...
Quan Gao, Fan Li, Jiajie Gao, Elric Zhang, Yingdong Su, Ni Qin, Hao Ye, Josep Puigmartí, Giuseppe Cantarella, Simone Schuerle, Jiang Wu, Bradley J. Nelson, Salvador Pané   +12 more
wiley   +1 more source

Unusual Swelling Behavior of Hydrogels Modified with Spiropyran as Appendage or Crosslinker

Advanced Functional Materials, EarlyView.
Not so innocent after all—spiropyran crosslinkers in methylenebisacrylamide‐crosslinked poly(acrylamide‐co‐acrylic acid) hydrogels increase crosslinking density, but also, counterintuitively, increase swelling. Charge complexation, cooperative chemo‐mechanical effects, and aggregation may explain these observations.
Michael M. Lerch, Ankita Shastri, Thomas B. H. Schroeder, Amos Meeks, Shucong Li, Anna V. Shneidman, Michael Aizenberg, Joanna Aizenberg   +7 more
wiley   +1 more source

Utilization of Okra Stem Waste Extracts for the Development of Dual Network and Self-Healing Polysaccharide/Gelatin Hydrogels With Natural Crosslinker Succinic Acid

International Journal of Polymer Science
In this study, okra gum polysaccharides derived from okra stem waste extract were utilized as a raw material for synthesizing hydrogel matrices. The polysaccharide-rich okra gum was combined with gelatin to enhance the gelation properties of the ...
Emine Dilara Kocak, Giada Dammacco, Nursema Pala, Alessandra Operamolla, Filippo Pagliai, Cagatay Gumus, Ozgur Atalay   +6 more
doaj   +1 more source

A New Self-Healing Hydrogel Containing hucMSC-Derived Exosomes Promotes Bone Regeneration

Frontiers in Bioengineering and Biotechnology, 2020
BackgroundFractures are a medical disease with a high incidence, and about 5–10% of patients need bone transplantation to fill the defect. In this study, we aimed to synthesize a new type of coralline hydroxyapatite (CHA)/silk fibroin (SF)/glycol ...
Li Wang, Li Wang, Jian Wang, Xiangbin Zhou, Jie Sun, Biao Zhu, Cuimi Duan, Peng Chen, Ximin Guo, Tong Zhang, Hongyan Guo, Hongyan Guo   +11 more
doaj   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

4D Printing of Self‐Immolative Polymers

Advanced Functional Materials, EarlyView.
The integration of self‐immolative polymers (SIPs) into light‐based 3D printed structures is presented as a new “living” 4D printing strategy. By exploiting their metastability and stimuli‐responsiveness, SIP‐containing printed objects can undergo rapid and triggered degrowth under ambient conditions and subsequent regrowth through polymer ...
Johannes Markhart, Philipp Mainik, Pia S. Klee, Eva Blasco   +3 more
wiley   +1 more source

Potential use of fly ash based nano silica as mineral additive to improve the mechanical properties of self-healing mortar

Case Studies in Construction Materials
Hydrogel-based self-healing mortar often experiences strength decrease that may impact concrete performance under mechanical load. While the addition of commercial colloidal nano silica can improve the strength of hydrogel-based self-healing mortar, they
Puput Risdanareni, Vita Ayu Kusuma Dewi, Ruri Agung Wahyuono, Januarti Jaya Ekaputri, Monita Olivia, Yaghoob Farnam, Nele De Belie   +6 more
doaj   +1 more source