Results 111 to 120 of about 4,830,480 (261)

Self-Healing and Shape-Memory Hydrogels

Hacettepe Journal of Biology and Chemistry, 2020
Hydrogels are soft and smart materials with great similarity to biological systems. In the past decade, a significant progress has been achieved to produce mechanically strong and tough hydrogels. Another major challenge in gel science is to generate self-healing and shape-memory functions in hydrogels to extend their application areas.
openaire   +3 more sources

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Preparation and characterization of self-healing nanocomposite hydrogels based on chitosan/polyethylene glycol/bacterial nanocellulose for wound dressing applications

Scientific Reports
Hydrogels used for wound dressing applications often suffer from limited mechanical stability and insufficient self-repair capability, which restricts their long-term performance in dynamic physiological environments.
Shiva Soori, Niloofar Eslahi, Reza Jahanmardi   +2 more
doaj   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Zwitterionic Polymer Coating Enabled Chronic Dopamine Sensing and Electrophysiology Recording in Free‐Moving Mice

Advanced Healthcare Materials, EarlyView.
Application of a zwitterionic poly(sulfobetaine methacrylate) (PSB) coating to microelectrode arrays and Ag/AgCl reference electrodes effectively inhibits biofouling and structural degradation. This strategy successfully enables simultaneous, long‐term electrophysiological recording and dopamine sensing in freely behaving mice, facilitating ...
Bingchen Wu, Cort Thompson, Thomas Deakin, Yan Xu, Colleen A. McClung, Xinyan Tracy Cui   +5 more
wiley   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Development of Clindamycin-Releasing Polyvinyl Alcohol Hydrogel with Self-Healing Property for the Effective Treatment of Biofilm-Infected Wounds

Gels
Self-healing hydrogels have good mechanical strength, can endure greater external force, and have the ability to heal independently, resulting in a strong bond between the wound and the material.
Nur Alifah, Juliana Palungan, Kadek Ardayanti, Muneeb Ullah, Andi Nokhaidah Nurkhasanah, Apon Zaenal Mustopa, Subehan Lallo, Rina Agustina, Jin-Wook Yoo, Nurhasni Hasan   +9 more
doaj   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Solvent-based self-healing polymeric materials [PDF]

, 2010
Mechanical damage to bulk polymers typically begins as a microcrack, which can lead to eventual failure of the material if there is no method to inhibit crack growth. In living systems, this damage automatically initiates a healing response.
Caruso, Mary M.
core  

Overview of Dynamic Bond Based Hydrogels for Reversible Adhesion Processes

Gels
Polymeric hydrogels are soft materials with a three-dimensional (3D) hydrophilic network capable of retaining and absorbing large amounts of water or biological fluids.
Ilaria Condò, Sara Maria Giannitelli, Daniela Lo Presti, Barbara Cortese, Ornella Ursini   +4 more
doaj   +1 more source