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Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra +3 more
wiley +1 more source

The “Diagnosis of Personal and Professional Feasibility” Methodology: Structure and Psychometric Justification

Bulletin of Kharkiv National University of Internal Affairs
The article presents the results of the development and psychometric testing of the author’s methodology “Diagnostics of personal and professional feasibility”, which is a tool for comprehensive assessment of personal and professional components of ...
Ya. S. Ponomarenko
doaj +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack +39 more
wiley +1 more source

Generational Communities in Higher Education: Selection Criteria, Self-Identification and Role in the Stability of the University

Высшее образование в России
Solving the problems of modern Russian higher education requires the search for new methodological approaches. Such an approach can be a generational approach.
N. V. Shabrova
doaj +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda +15 more
wiley +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source

CENTAUR-PARADOXES OF ECONOMIC CONSCIOUSNESS OF RUSSIAN ENTREPRENEURSHIP

Вестник Донского государственного технического университета, 2018
Basic coordinates of the economic consciousness of the Russian business are considered. It is revealed, that subjectlessness, expolarity, diffusion of the Russian economy have formed multidirectional attitudes in the economic consciousness of business ...
Mikhail N. Mikheyev
doaj

Principles of privacy and safety in the design of Syrian orphanages

Архитектон
The analysis of existing orphanages in the city of Aleppo revealed the predominant use of an institutional model in the formation of the architectural volume, which contributes to the isolation of the child from the social community of the city, does not
Akeel Aya, Anisimova Liudmila V.
doaj +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

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