Results 51 to 60 of about 4,459,273 (155)

Control of Gemcitabine Activity With Blue and Red Light

open access: yesChemistry – A European Journal, EarlyView.
Treating cancer with chemotherapy is generally associated with many side effects, which can be addressed by selectively releasing the desired drugs with visible light. Sixteen new blue light‐activatable cytostatics were introduced, with the gemcitabine derivative exhibiting ideal properties.
Nils F. Kersten   +6 more
wiley   +1 more source

Prevalence of causes of suicide in Zabol [PDF]

open access: yesPatient Safety and Quality Improvement Journal
Introduction: Suicide is an act intentionally carried out by an individual to harm themselves, fully aware of the consequences. Emotional and relational factors also play a significant role in suicide attempts.
Seyed Ali Forghani   +4 more
doaj   +1 more source

Cellular Membrane‐Targeted Europium(III) Probe for Selective and Time‐Resolved Detection of Peroxynitrite

open access: yesChemistry – A European Journal, EarlyView.
We report a cellular membrane‐targeted europium(III) probe, Eu.Chol, that enables selective, time‐resolved detection of peroxynitrite (ONOO−) at the cell membrane interface. Eu.Chol demonstrates efficient incorporation into liposomes and Jurkat cells, with minimal response to H2O2, establishing a modular platform for subcellular ONOO− sensing ...
Jamie Webb   +6 more
wiley   +1 more source

Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs

open access: yesAngewandte Chemie, Volume 138, Issue 40, 28 September 2026.
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang   +7 more
wiley   +2 more sources

Population Level Impact of Self-Immolation on Burn Unit Resources: A Retrospective Case-Matched Study [PDF]

open access: yes, 2021
Background: This investigator sought to enhance medical knowledge and clinical care by distinguishing the population level characteristics of patients who attempted self-immolation within the burn population and determine the impact these patients have ...
Bolling, Kristina Rosa Cruz
core   +1 more source

30th anniversary in Vytautas Magnum university of Romas Kalanta selfburn

open access: yesGenocidas ir Rezistencija, 2002
The 30th anniversary of self-immolation of Romas Kalanta was commemorated by hosting various events. The scientific conference titled Kaunas in 1972: Alternative Culture, Political Protest and Cultural Resistance organised by the History Department of ...
Arūnas Streikus
doaj   +1 more source

Self‐Immolative Poly(Benzyl Ether)s: Design Principles and Controlled Depolymerization

open access: yesChemistry – A European Journal, EarlyView.
Unzipping to Sustainability: This Concept article explores the thermodynamic design of quinone‐methide (QM)‐based poly(benzyl ether)s (PBEs). It explains how a low ceiling temperature (Tc), QM stability, and an entropic gain drive rapid depolymerization (“unzipping”) of PBEs into monomers.
Ji Woo Kim, Yewon Kang, Hyungwoo Kim
wiley   +1 more source

Reflections on Self-Immolation in Chinese Buddhist and Daoist Traditions

open access: yes, 2018
This chapter explores self-immolation in the premodern Chinese Buddhist and Daoist historical milieus. It historicizes this ritual within the spectrum of wider Indian Buddhist practices, and explores the Chinese (and by extension, East Asian) imagination
Jimmy Yu
core   +1 more source

Nitro Reduction‐Based RNA Control and Ultrafast Release

open access: yesAngewandte Chemie, Volume 138, Issue 40, 28 September 2026.
A chemical RNA caging–uncaging strategy based on nitro reduction is described. Nitroaryl groups introduced via acylation temporarily block the functions of diverse RNAs in vitro and in living cells. Treatment with a diboronic acid–bipyridine mixture rapidly reduces the nitro groups, releasing RNAs and restoring their activity.
Yiran Zhao   +6 more
wiley   +2 more sources

Factors associated with the choice of suicide method in Kermanshah Province, Iran

open access: yesAnnals of Saudi Medicine, 2016
BACKGROUND: Identification of factors in the choice of suicide methods is important in understanding the phenomenon. OBJECTIVES: We aimed to quantify the effect of gender, age, living area, education level and marital status on the choice of suicide ...
Mehran Rostami   +3 more
doaj   +1 more source

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