Mechanism of self/nonself-discrimination in Brassica self-incompatibility
Self-incompatibility responses in Brassica are induced by haplotype-specific interactions between the pistil-expressed SRK receptor and pollen-expressed SP11 ligand.
Kohji Murase +17 more
doaj +1 more source
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
Recent and Ancient Signature of Balancing Selection around the S-Locus in Arabidopsis halleri and A. lyrata [PDF]
Balancing selection can maintain different alleles over long evolutionary times. Beyond this direct effect on the molecular targets of selection, balancing selection is also expected to increase neutral polymorphism in linked genome regions, in inverse ...
Ruggiero, Maria-Valeria +10 more
core +1 more source
Review of the self-incompatibility in apple (Malus x domestica Borkh., syn.: Malus pumila Mill.)
Apple (Malus x domestica Borkh.) is one of the most important fruit crops showing ribonuclease-mediated self-incompatibility, and no self-compatible apple cultivars are known.
A. Hegedűs
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Independent S-locus mutations caused self-fertility in Arabidopsis thaliana. [PDF]
A common yet poorly understood evolutionary transition among flowering plants is a switch from outbreeding to an inbreeding mode of mating. The model plant Arabidopsis thaliana evolved to an inbreeding state through the loss of self-incompatibility, a ...
Nathan A Boggs +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The molecular biology of self-incompatibility in Brassica [PDF]
Self- incompatibility in Brassica is controlled by a single "S"-locus. Different self- incompatible genotypes of Brassica are correlated with the occurrence of S-locus-specific glycoproteins (SLSGs), cDNA sequences for certain of which have been ...
Scutt, Charles Patrick, Scutt, C.P
core
Self-incompatibility in Papaver targets soluble inorganic pyrophosphatases in pollen
In higher plants, sexual reproduction involves interactions between pollen and pistil. A key mechanism to prevent inbreeding is self-incompatibility through rejection of incompatible ('self') pollen(1). In Papaver rhoeas, S proteins encoded by the stigma
F. Christopher H. Franklin +25 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source

