Results 61 to 70 of about 4,621 (264)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Leakage Inductances of Transformers at Arbitrarily Located Windings

Energies, 2020
The article presents the calculation of the leakage inductance in power transformers. As a rule, the leakage flux in the transformer window is represented by the short-circuit inductance, which affects the short-circuit voltage, and this is a very ...
Marcin Jaraczewski, Tadeusz Sobczyk
doaj   +1 more source

Name for Unit of Self-Induction [PDF]

Nature, 1889
A NAME for the unit coefficient of self-induction is much wanted. No one is satisfied with secohm, and yet it seems making its way; by reason, no doubt, of Ayrton and Perry's ingenious commutating arrangement for helping to measure it. It is an unpleasing name, and it is too big a unit.
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Nominal and Actual Values of Inductor and Capacitor Parameters at High Frequencies

Российский технологический журнал, 2019
Coil inductance and capacitor capacitance depend on overall dimensions, structure, and ambient factors. They do not vary with frequency. Reactive component impedance is determined by inductance or capacitance respectively, if active resistance is not ...
E. V. Gurov, S. S. Uvaysov, A. S. Uvaysova, S. S. Uvaysova   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Optimization of Magnetic Core Structures for Enhanced Magnetic Coupling in Helical Coil Inductive Power Transmission

Energies
Inductive power transfer (IPT) systems often encounter limitations in efficiency and transmission distance due to near-field magnetic coupling characteristics. Increasing the inductance can enhance the transmission distance, but it also raises the system’
Ho-Yeong Lee, Seung-Ahn Chae, Min-Seung Song, Gwan-Soo Park   +3 more
doaj   +1 more source

Optical properties of metamaterial serpentine metal electrodes

AIP Advances, 2014
We develop a model to describe the optical properties of periodic surpentine structures in the metamaterial regime. The structures are essentially transparent to infrared radiation and would be useful for transparent electrodes. The model predictions for
Sang Eon Han, Samuel M. Clark
doaj   +1 more source