Results 101 to 110 of about 517,211 (382)

Effectiveness and safety of baricitinib for juvenile idiopathic arthritis associated uveitis or chronic anterior antinuclear antibody positive uveitis

open access: yesArthritis Care &Research, Accepted Article.
Objectives Evaluate the efficacy and safety of baricitinib in paediatric patients with active JIA‐U or chronic anterior ANA‐positive uveitis, who had an inadequate response to MTX or bDMARDs. Methods JUVE‐BRIGHT was an open‐label, active‐controlled, Phase‐3 multicentre trial which utilized a novel design, including 1:1 randomization to an active ...
Athimalaipet V. Ramanan   +7 more
wiley   +1 more source

Clinical and theoretical issues in self-injurious behavior

open access: yesBrazilian Journal of Psychiatry, 1999
This article presents an overview of pathological self-injurious behavior (SIB). Historical and cultural aspects, epidemiology, classification and clinical aspects and pathogenesis are described.
Jose A. Yaryura-Tobias   +2 more
doaj   +1 more source

Effective Interventions for Treating Superficial Self Mutilators [PDF]

open access: yes, 2008
Self-cutting is the most common form of self-mutilation in adolescents but there is insufficient knowledge as to which treatment methods to reduce self-mutilation are most effective.
Palladini, Maria
core   +1 more source

The effect of foot orthoses on midfoot pain and the volume of bone marrow lesions in the midfoot: a randomized mechanism of action study

open access: yesArthritis Care &Research, Accepted Article.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain and MRI‐confirmed midfoot BMLs.
Jill Halstead   +4 more
wiley   +1 more source

The Link Between Dissociation, Eating Disorders, and Self-Harm [PDF]

open access: yes, 2014
Many researchers and psychological professionals believe that there is a link between eating disorders and self-harm, though this has been less widely researched than other correlations such as that between eating disorders and substance abuse.
Zimmerman, Amy A
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

The impact of childhood sexual, physical and emotional abuse and neglect on suicidal behavior and non-suicidal self-injury: A systematic review of meta-analyses

open access: yesPsychiatry Research Communications
Self-injurious thoughts and behavior, encompassing suicidal ideation, attempts and non-suicidal self-injury, represent a critical global health concern. Amidst the multifaceted nature of these behaviors and the various underlying risk factors, childhood ...
Alicia Y.Y. Chia   +5 more
doaj   +1 more source

Sociological Seminar Senior Thesis A Comparison Study of Causal Factors Contributory to Self-Mutilation [PDF]

open access: yes, 2004
Self-injurious behavior has become an increasingly well known phenomenon in today\u27s society. By way of comparing factors leading up to and purposes derived from the self-injurious behavior, this paper compares the life story of one self-proclaimed ...
Kiel, Jamy
core   +1 more source

Using the validated Reflective Functioning Questionnaire to investigate mentalizing in individuals presenting with eating disorders with and without self-harm [PDF]

open access: yes, 2018
Background The present study builds on previous research which explored the relationship between mentalizing and eating disorders (ED) in a subgroup of patients with comorbid self-harm (SH).
Cucchi, A.   +2 more
core   +2 more sources

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage Polarization

open access: yesAdvanced Biology, EarlyView.
This study explores the use of collagen‐hyaluronic acid (HA) hydrogels for the 3D culture of macrophages, providing a useful tool for modelling macrophage behavior in tissues and diseases. It highlights how hydrogel composition, mechanical properties, and preparation methods influence macrophage behavior, revealing for the first time that HA's ...
Tiah CL Oates   +7 more
wiley   +1 more source

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