Results 31 to 40 of about 9,762,699 (265)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Impact of information publicity on Korean residents’ E-waste recycling intentions: Applying the norm activation model and theory of planned behavior

Heliyon
The escalating annual growth rate of electronic waste, commonly referred to as “e-waste,” is currently between 3 % and 5 %, indicating a rapidly increasing solid waste stream. In 2019, South Korea generated 15.8 kg of e-waste per capita. The expansion of
Walimuni Arachchilage Chathuri Sugandika Muthukumari, Jinhyun Ahn, Mincheol Kim   +2 more
doaj   +1 more source

Epilepsy and Self-Management

, 2016
Epilepsy is a chronic disease. A high quality of life can be achieved when seizures are controlled, requiring important behavioral and psychosocial adjustments.

core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Pain and Cognitive Concerns Among Breast Cancer Survivors: The Mediating Role of Substance Use Coping

Cancer Medicine
Context Bodily pain and cognitive concerns are both prevalent and share similar underlying mechanisms. A few studies have suggested that pain and cognitive concerns may be linked through substance use coping; however, this relationship remains unclear ...
Yesol Yang, Alai Tan, Leorey N. Saligan, Diane Von Ah   +3 more
doaj   +1 more source

Assessing the impact of sustainability report disclosures and CEO attributes on the Indonesian energy sector: implications for capital market performance

Cogent Business & Management
The growth of the world energy market is experiencing a slowdown moment in line with the decline in demand due to the COVID-19 pandemic. While Indonesia has the potential for energy resources and natural resources which are very diverse and abundant, on ...
Ayi Ahadiat, Amjad Shamim, Habibullah Jimad, Fajrin Satria Dwi Kesumah   +3 more
doaj   +1 more source

Race-Related Differences Between and Within Sex to Experimental Thermal Pain in Middle and Older Adulthood: An Exploratory Pilot Analysis

Frontiers in Pain Research, 2021
This brief report details a pilot analysis conducted to explore racial differences in pain sensitivity and unpleasantness between cognitively healthy Black and White adults, stratified by sex.
Karen O. Moss, Karen O. Moss, Karen O. Moss, Kathy D. Wright, Kathy D. Wright, Kathy D. Wright, Alai Tan, Karen M. Rose, Karen M. Rose, Douglas W. Scharre, Douglas W. Scharre, Tanya R. Gure, Tanya R. Gure, Ronald L. Cowan, Michelle D. Failla, Michelle D. Failla, Todd B. Monroe, Todd B. Monroe   +17 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Co-creating cultures of sustainability and co-imagining the teaching green building: the use of a participatory Photovoice process in a HPGB context

Sustainable Earth Reviews, 2022
Plain English Summary There is not enough action to address the global challenge of climate change, despite understanding how severe this crisis is.
Kai Reimer-Watts, Esther Abel, Simon Coulombe, Manuel Riemer   +3 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source