Results 61 to 70 of about 1,370,207 (289)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

KETERKAITAN DIABETES SELF MANAGEMENT EDUCATION TERHADAP SELF EFFICACY PASIEN DIABETES MELLITUS

Jurnal Keperawatan, 2015
KETERKAITAN DIABETES SELF MANAGEMENT EDUCATION TERHADAP SELF EFFICACY PASIEN DIABETES MELLITUS The Connection of Diabetes Self Management Education With Self Efficacy Diabetes Mellitus Patient Rondhianto Program Studi Ilmu Keperawatan Universitas ...
Rondhianto .
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Synergistic effects of family members as caregivers after acute hemorrhagic stroke in Jeju: a preliminary cohort study in Jeju, Korea

BMC Neurology
Objective All patients with hemorrhagic stroke aspire to recover to their pre-stroke condition. Their initial condition is often poor, but neurological status gradually improves in the absence of postictal complications.
Hyun Jeong Lee, Eun-Hee Lee, Jin-Deok Joo, You Nam Chung, Hyeung-Keun Park, Sang Hyung Lee, Ji Soon Huh, Jong-Kook Rhim   +7 more
doaj   +1 more source

Maximal isokinetic elbow and knee flexor–extensor strength measures in combat sports athletes: the role of movement velocity and limb side

BMC Sports Science, Medicine and Rehabilitation, 2022
Background Maximal isokinetic strength ratios of joint flexors and extensors are important parameters to indicate the level of muscular balance at the joint. Further, in combat sports athletes, upper and lower limb muscle strength is affected by the type
Said El-Ashker, Helmi Chaabene, Olaf Prieske   +2 more
doaj   +1 more source

Predictors of Engagement in Postpartum Weight Self-management Behaviours in the First 12 Weeks After Birth [PDF]

, 2015
Aim To explore factors that influence postpartum weight self-management behaviours. Transitions Theory and the Integrated Theory of Health Behaviour Change guided selection of variables.
Ohlendorf, Jennifer, Oswald, Debra, Weiss, Marianne E.   +2 more
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Intelligent Diagnosis Method for Typical Co-frequency Vibration Faults of Rotating Machinery Based on SAE and Ensembled ResNet-SVM

Chinese Journal of Mechanical Engineering
Intelligent fault diagnosis is an important method in rotating machinery fault diagnosis and equipment health management. To deal with co-frequency vibration faults, a type of typical fault in rotating machinery, this paper proposes a fault diagnosis ...
Xiancheng Zhang, Xin Pan, Hao Zeng, Haofu Zhou   +3 more
doaj   +1 more source

SELF MANAGEMENT PROGRAM MENINGKATKAN KOPING, NIAT DAN KEPATUHAN BEROBAT PASIEN PJK SETELAH PEMBERIAN SELF MANAGEMENT PROGRAM

Jurnal Ners, 2016
Introduction: Management coronary artery disease required lifelong treatment. The successful management of CHD requires efective coping, intention and medication adherence of CHD’s patients.
Hanim mufarokhah mufarokhah, Suhartono Putra, Yulis Dewi   +2 more
doaj   +1 more source

Self-Management

Social Sciences and Education Research Review
Abstract This chapter presents how motivational interviewing (MI) can be incorporated to support patients in the process of self-management. Effective self-management, such as medical, emotional, and role management, is essential to optimizing health outcomes for people with chronic conditions.
Danbi Lee, Maureen Gecht-Silver, Linda Ehrlich-Jones   +2 more
  +5 more sources