Results 61 to 70 of about 626,642 (251)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Qualitative analysis of out-of-hospital self-management capabilities and ongoing care needs in patients with gynecological malignancies and venous thromboembolism

Annals of Medicine
Background Postoperative patients with gynecological malignant tumors are prone to venous thromboembolism (VTE) due to hypercoagulability and limited mobility, and lack of professional guidance after discharge, further increasing the risk of VTE ...
Tian-Hua Li, Yan-Wei Wang, Jing-Xuan Feng, Ning Sun, Ya-Jing Bian, Jun-Ying Ma, Lai-You Li   +6 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Construction and effect evaluation of extended integrative nursing model for patients with diabetic retinopathy (糖尿病视网膜病变患者中西医延续护理模式的构建及效果评价)

中西医结合护理
Objective To explore the construction and effect of the extended integrative nursing model for patients with diabetic retinopathy (DR). Methods A total of 100 DR Patients treated in our hospital from August 2024 to February 2025 were selected and ...
WANG Qiao (王俏), LIN Zihan (林姿含), LI Jing (李静)   +2 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A shared decision-making approach to individualized exercise management enhances glycemic control, self-care behaviors, and quality of life in type 2 diabetes: a retrospective cohort study

Frontiers in Public Health
ObjectiveTo evaluate the association between an individualized exercise management program based on shared decision-making (SDM) and short-term glycemic control, self-care behaviors, and quality of life in patients with type 2 diabetes mellitus (T2DM ...
Tingting Feng, Fengcheng Cai, Shuangyan Xu   +2 more
doaj   +1 more source

Evaluation of self⁃management ability of patients with chronic diseases based on close⁃value method and rank⁃sum ratio method

Huli yanjiu, 2021
ObjectiveTo evaluate self⁃management ability of patients with chronic diseases based on close⁃value method and rank⁃sum ratio method，and to provide basis for formulating targeted health education and health promotion measures.MethodsSelf-management ...
YAN Beilei, LIU Junjun, YANG Chen, WANG Gaoling   +3 more
doaj  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source