Results 61 to 70 of about 592,549 (248)

Impact of empowerment guidance on discharge readiness and self-management ability in elderly patients at high risk of falls

Guoji laonian yixue zazhi
[Objective] To investigate the effect of empowerment guidance on readiness for discharge and self-management ability in elderly patients at high risk of falls.
Jinglin Cao, Yuehui Wang, Ying Li, Weixin Huang   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Development of self-management ability in research activities in teachers to-be

Вестник Северо-Кавказского федерального университета
Introduction. The social order of the pedagogical education system is aimed at forming independent experience in research activities (R&D) in future teachers, which made it possible to emphasize the relevance of the problem of developing third-year students’ ability for self-management of the individual as a result of writing a final qualifying ...
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Key management scheme with private key self-healing ability in DTN

网络与信息安全学报, 2017
Because of the large delay of DTN network,node cannot receive broadcast updating private key messages in a timely manner,thus unable to update the private key for a certain time period.Aiming at this problem,an allowing private key self-healing ...
De-quan LI,Xi-yong ZHANG,Ting-ting ZHANG, Guan-jun GUO   +1 more
doaj   +3 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Meta-Learning: Concept Analysis

Acta Paedagogica Vilnensia, 2020
Meta-learning, a contemporary learning paradigm, will be analysed in this article. This study aims to analyse and conceptualize the definition of metalearning, to provide evidence for the application of metalearning to learning, and to single out and ...
Jovita Matulaitienė, Lina Kaminskienė   +1 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Risk perception level of chronic kidney disease and related factors in patients with type 2 diabetes mellitus

Zhongguo linchuang yanjiu
Objective To explore the risk perception level of chronic kidney disease (CKD) and its related factors in patients with type 2 diabetes mellitus (T2DM), so as to enhance their awareness of CKD prevention and control.
WANG Yaling*, YANG Fangting, WANG Huili, ZHANG Ling, ZHANG Junrong, XIAO Jiangqin
doaj   +1 more source